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用于生物医学传感应用的三波段高灵敏度太赫兹超材料吸收器。

Triple-band highly sensitive terahertz metamaterial absorber for biomedical sensing applications.

作者信息

Miah Asad, Al Zafir Sams, Hasnain Md, Das Joyonta, Haque Sayed Muhammad Anowarul, Wahed Abdul

机构信息

Department of Electrical and Electronic Engineering, Mymensingh Engineering College, Mymensingh, Bangladesh.

出版信息

PLoS One. 2025 Aug 19;20(8):e0328077. doi: 10.1371/journal.pone.0328077. eCollection 2025.

Abstract

Due to the growing interest in metamaterials for biomedical applications, this study presents the design and analysis of a novel, compact, triple-band metamaterial absorber for biological sensing in the terahertz range. The structure, with dimensions of 41 × 41 μm2, exhibits exceptionally high absorption rates above 99% at three distinct resonance frequencies of 1.85, 3.62, and 5.63 THz. To validate the design, an equivalent circuit model was created and evaluated alongside electric field, magnetic field, and surface current distributions. A key focus of this work is the sensor's performance, evaluated by introducing a sensing layer with varying refractive indices. The absorber demonstrates outstanding sensitivity values of 1.5 THz/RIU, 1 THz/RIU, and 0.66 THz/RIU at the third, second, and first resonances, respectively, indicating highly reliable sensing performance across multiple frequency bands. Furthermore, its suitability for biochemical applications was evaluated by testing its ability to detect different samples, such as glucose, malaria, and cervical cancer cells. The absorber also demonstrates strong performance metrics, with a maximum quality factor of 39.13 and a figure of merit (FoM) of 6.95, supporting its reliability. Additionally, its suitability for microwave imaging (MWI) technology is also examined. The combination of near-perfect absorption and high sensitivity makes this compact metamaterial absorber a promising candidate for advanced biomedical sensing and diagnostic technologies.

摘要

由于对用于生物医学应用的超材料的兴趣日益浓厚,本研究提出了一种新颖、紧凑的三频段超材料吸收器的设计与分析,用于太赫兹范围内的生物传感。该结构尺寸为41×41μm²,在1.85、3.62和5.63太赫兹这三个不同的共振频率下,吸收率超过99%。为验证该设计,创建了一个等效电路模型,并结合电场、磁场和表面电流分布进行评估。这项工作的一个关键重点是传感器的性能,通过引入具有不同折射率的传感层进行评估。该吸收器在第三、第二和第一共振频率下分别表现出1.5太赫兹/RIU、1太赫兹/RIU和0.66太赫兹/RIU的出色灵敏度值,表明在多个频段具有高度可靠的传感性能。此外,通过测试其检测不同样本(如葡萄糖、疟疾和宫颈癌细胞)的能力,评估了其在生化应用中的适用性。该吸收器还展示了强大的性能指标,最大品质因数为39.13,品质因数(FoM)为6.95,证明了其可靠性。此外,还研究了其对微波成像(MWI)技术的适用性。近乎完美的吸收和高灵敏度的结合,使这种紧凑的超材料吸收器成为先进生物医学传感和诊断技术的有前途的候选者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ee6/12364324/b4acd686aea2/pone.0328077.g001.jpg

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