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骨科革命:纳米技术的新兴作用。

Orthopedic revolution: The emerging role of nanotechnology.

作者信息

Ruan Wen-Jie, Xu Si-Si, Xu Dong-Hui, Li Zhi-Peng

机构信息

Department of Sports Medicine, Zhejiang Provincial People's Hospital (The Affiliated People's Hospital), Hangzhou 310000, Zhejiang Province, China.

School of Medicine, Taizhou University, Taizhou 318000, Zhejiang Province, China.

出版信息

World J Orthop. 2024 Oct 18;15(10):932-938. doi: 10.5312/wjo.v15.i10.932.

DOI:10.5312/wjo.v15.i10.932
PMID:39473517
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11514548/
Abstract

This review summarizes the latest progress in orthopedic nanotechnology, explores innovative applications of nanofibers in tendon repair, and evaluates the potential of selenium and cerium oxide nanoparticles in osteoarthritis and osteoblast differentiation. This review also describes the emerging applications of injectable hydrogels in cartilage engineering, emphasizing the critical role of interdisciplinary research and highlighting the challenges and future prospects of integrating nanotechnology into orthopedic clinical practice. This comprehensive approach provides a holistic perspective on the transformative impact of nanotechnology in orthopedics, offering valuable insights for future research and clinical applications.

摘要

本综述总结了骨科纳米技术的最新进展,探讨了纳米纤维在肌腱修复中的创新应用,并评估了氧化硒和氧化铈纳米颗粒在骨关节炎和成骨细胞分化中的潜力。本综述还描述了可注射水凝胶在软骨工程中的新兴应用,强调了跨学科研究的关键作用,并突出了将纳米技术整合到骨科临床实践中的挑战和未来前景。这种全面的方法提供了关于纳米技术在骨科领域变革性影响的整体观点,为未来的研究和临床应用提供了有价值的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6313/11514548/cbebabf21e2b/WJO-15-932-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6313/11514548/cbebabf21e2b/WJO-15-932-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6313/11514548/cbebabf21e2b/WJO-15-932-g001.jpg

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本文引用的文献

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NSAID: Current limits to prescription.非甾体抗炎药:处方的现行限制。
Joint Bone Spine. 2024 Jul;91(4):105685. doi: 10.1016/j.jbspin.2023.105685. Epub 2023 Dec 29.
2
Injectable hydrogel with selenium nanoparticles delivery for sustained glutathione peroxidase activation and enhanced osteoarthritis therapeutics.用于持续激活谷胱甘肽过氧化物酶并增强骨关节炎治疗效果的载硒纳米颗粒可注射水凝胶。
Mater Today Bio. 2023 Nov 11;23:100864. doi: 10.1016/j.mtbio.2023.100864. eCollection 2023 Dec.
3
Silver nanoparticle technology in orthopaedic infections.
骨科感染中的银纳米颗粒技术。
World J Orthop. 2023 Sep 18;14(9):662-668. doi: 10.5312/wjo.v14.i9.662.
4
Nanomedicine in cancer therapy.癌症治疗中的纳米医学。
Signal Transduct Target Ther. 2023 Aug 7;8(1):293. doi: 10.1038/s41392-023-01536-y.
5
The Protective Effect of Selenium Nanoparticles in Osteoarthritis: In vitro and in vivo Studies.硒纳米粒子在骨关节炎中的保护作用:体外和体内研究。
Drug Des Devel Ther. 2023 May 22;17:1515-1529. doi: 10.2147/DDDT.S407122. eCollection 2023.
6
Sustained intra-articular reactive oxygen species scavenging and alleviation of osteoarthritis by biocompatible amino-modified tantalum nanoparticles.生物相容性氨基修饰钽纳米颗粒持续清除关节内活性氧并缓解骨关节炎
Front Bioeng Biotechnol. 2023 Jan 13;11:1118850. doi: 10.3389/fbioe.2023.1118850. eCollection 2023.
7
Clinical effect and biological mechanism of exercise for rheumatoid arthritis: A mini review.运动治疗类风湿关节炎的临床疗效及生物学机制:小型综述。
Front Immunol. 2023 Jan 6;13:1089621. doi: 10.3389/fimmu.2022.1089621. eCollection 2022.
8
Advanced injectable hydrogels for cartilage tissue engineering.用于软骨组织工程的先进可注射水凝胶。
Front Bioeng Biotechnol. 2022 Sep 8;10:954501. doi: 10.3389/fbioe.2022.954501. eCollection 2022.
9
Therapeutic Ultrasound and Shockwave Therapy for Tendinopathy: A Narrative Review.治疗性超声与冲击波疗法治疗腱病:叙述性综述。
Am J Phys Med Rehabil. 2022 Aug 1;101(8):801-807. doi: 10.1097/PHM.0000000000001894. Epub 2021 Oct 4.
10
Advanced Nanofiber-Based Scaffolds for Achilles Tendon Regenerative Engineering.用于跟腱再生工程的先进纳米纤维基支架
Front Bioeng Biotechnol. 2022 Jun 30;10:897010. doi: 10.3389/fbioe.2022.897010. eCollection 2022.