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加拿大移民中乙型和丙型肝炎的估计患病率。

Estimated prevalence of hepatitis B and C among immigrants in Canada.

作者信息

Campeau Laurence, Elliott Janelle, Williams Anson, Périnet Simone, Yang Qiuying, Cox Joseph, Feld Jordan J, Greenaway Christina, Popovic Nashira

机构信息

Public Health Agency of Canada, Ottawa, ON.

Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, QC.

出版信息

Can Commun Dis Rep. 2025 Jul 1;51(6-7):214-222. doi: 10.14745/ccdr.v51i67a01. eCollection 2025 Jul.

Abstract

BACKGROUND

Canada's Sexually Transmitted and Blood-borne Infections (STBBI) Action Plan and the Global Health Sector Strategies on STBBI highlight the importance of putting people at the centre of the health system response. Several key populations are disproportionately affected by viral hepatitis, including immigrants. However, there is a limited body of evidence on the burden of viral hepatitis among immigrants in Canada. We seek to address this gap by estimating the prevalence of hepatitis B (HBV) and C (HCV) infections among immigrants in Canada.

METHODS

Using country- and region-specific publicly available data on the prevalence of HBV and HCV, we estimated the number of immigrants with chronic HBV (CHB), HCV antibodies, and chronic HCV (CHC) by multiplying the number of immigrants from Statistics Canada's 2021 census of population data by the corresponding publicly available country or region-of-origin prevalence, including lower and upper bounds. Each country was categorized as low (<2%) or intermediate-to-high (≥2%) based on published prevalence. To capture changes over time, estimates were stratified by time-period, where possible.

RESULTS

In 2021, the estimated prevalence of viral hepatitis among all immigrants was 4.03% for CHB, 1.43% for HCV antibodies, and 0.78% for CHC. The estimated prevalence of CHB, HCV antibodies, and CHC was 0.91%, 0.96% and 0.52%, respectively, among immigrants from low-prevalence countries (<2%). It was 5.57%, 4.04%, and 2.20%, respectively, among immigrants from intermediate-to-high-prevalence countries (≥2%).

CONCLUSION

This is the first study to estimate the burden of HBV and HCV among immigrants at the national level in Canada. The results show that the prevalence of viral hepatitis among immigrants is higher than the general Canadian population. However, grouping all immigrants into one category masks important variation, and potentially over-estimates the burden of HBV and HCV among immigrants. Strengthening our understanding of hepatitis prevalence among immigrants can improve our ability to connect those in need to care and treatment services.

摘要

背景

加拿大性传播和血源感染(STBBI)行动计划以及全球卫生部门关于STBBI的战略强调了将人置于卫生系统应对工作中心的重要性。包括移民在内的几个关键人群受病毒性肝炎的影响尤为严重。然而,关于加拿大移民中病毒性肝炎负担的证据有限。我们试图通过估计加拿大移民中乙型肝炎(HBV)和丙型肝炎(HCV)感染的患病率来填补这一空白。

方法

利用特定国家和地区公开的HBV和HCV患病率数据,我们通过将加拿大统计局2021年人口普查数据中的移民数量乘以相应公开的原籍国或地区患病率(包括下限和上限),来估计慢性HBV(CHB)、HCV抗体和慢性HCV(CHC)的移民数量。根据已公布的患病率,每个国家被分为低患病率(<2%)或中高患病率(≥2%)。为了了解随时间的变化,估计值在可能的情况下按时间段进行分层。

结果

2021年,所有移民中病毒性肝炎的估计患病率为CHB 4.03%、HCV抗体1.43%、CHC 0.78%。在低患病率国家(<2%)的移民中,CHB、HCV抗体和CHC的估计患病率分别为0.91%、0.96%和0.52%。在中高患病率国家(≥2%)的移民中,这一比例分别为5.57%、4.04%和2.20%。

结论

这是第一项在加拿大全国层面估计移民中HBV和HCV负担的研究。结果表明,移民中病毒性肝炎的患病率高于加拿大普通人群。然而,将所有移民归为一类掩盖了重要差异,并可能高估了移民中HBV和HCV的负担。加强我们对移民中肝炎患病率的了解可以提高我们将有需要的人与护理和治疗服务联系起来的能力。

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