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具有多尺度和多生物量传感功能的虚拟偏振器的理论设计

Theory Design of a Virtual Polarizer with Multiscale and Multi-Biomass Sensing.

作者信息

Wu Chuanqi, Zhang Haifeng

机构信息

College of Electronic and Optical Engineering & College of Flexible Electronics (Future Technology), Nanjing University of Posts and Telecommunications, Nanjing 210023, China.

出版信息

Biosensors (Basel). 2025 Aug 8;15(8):516. doi: 10.3390/bios15080516.

Abstract

Recently, more and more attention has been paid to human health with the rapid development of society. A designed virtual polarizer (VP) can realize multiscale and multi-biomass sensing, including temperature, cancerous cells, and COVID-19. Based on coherent perfect polarization conversion, a certain polarization conversion can be fulfilled within 1.72~2.14 THz. Then, through observing the displacement of a perfect matching point (PMP), variations in temperature can be accurately determined, covering from 299 K to 315 K, with a sensitivity () of 0.0198 THz/K. Moreover, a sharp coherent perfect absorption (CPA) peak generated from the VP can be employed for the detection of cancerous cells and COVID-19. The refractive index (RI) detection range of cancerous cells is from 1.36 RIU to 1.41 RIU with the sensitivity being -4.45881 THz/RIU. The average quality factor (), figure of merit (), and detection limit () are 825.36, 241.11 RIU, and -36.83 dB. For the COVID-19 solution concentration (SC) from 0 mM to 525 mM, by mapping SC to RI, the RI sensing range is 1.344 RIU-1.355 RIU with the being -5.03467 THz/RIU. The relevant , , and are 760.85, 244.94 RIU, and -36.89 dB. Based on two strategies of PMP and CPA, the proposed VP is capable of multiscale and multi-biomass sensing with excellent detection performance, providing a new detection method for biosensing.

摘要

近年来,随着社会的快速发展,人类健康越来越受到关注。一种设计的虚拟偏振器(VP)可以实现多尺度和多生物量传感,包括温度、癌细胞和新冠病毒。基于相干完美偏振转换,在1.72~2.14太赫兹范围内可以实现一定的偏振转换。然后,通过观察完美匹配点(PMP)的位移,可以准确确定温度变化,范围从299 K到315 K,灵敏度为0.0198太赫兹/开尔文。此外,VP产生的尖锐相干完美吸收(CPA)峰可用于检测癌细胞和新冠病毒。癌细胞的折射率(RI)检测范围为1.36 RIU至1.41 RIU,灵敏度为-4.45881太赫兹/RIU。平均品质因数()、品质因数()和检测限()分别为825.36、241.11 RIU和-36.83 dB。对于浓度为0 mM至525 mM的新冠病毒溶液浓度(SC),通过将SC映射到RI,RI传感范围为1.344 RIU - 1.355 RIU,灵敏度为-5.03467太赫兹/RIU。相关的、和分别为760.85、244.94 RIU和-36.89 dB。基于PMP和CPA两种策略,所提出的VP能够实现多尺度和多生物量传感,具有出色的检测性能,为生物传感提供了一种新的检测方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/475e/12384523/11c3a8462f19/biosensors-15-00516-g001.jpg

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