Fong Francis Jia Yi, Onggo Jason Derry, Munro Yasmin Lynda, Yam Michael Gui Jie
Tan Tock Seng Hospital, Singapore, Singapore.
Lee Kong Chian School of Medicine, Medical Library, Clinical Sciences Building (CSB), 20th Floor, 11 Mandalay Road, Singapore, 308232, Singapore.
Eur J Orthop Surg Traumatol. 2025 Aug 30;35(1):367. doi: 10.1007/s00590-025-04429-8.
In light of the increasing adoption of 3D printing in clinical practice, this review aims to provide an updated overview of the current applications of 3D printing in orthopedics and identify the gaps in existing literature.
An electronic database search of PubMed, Embase, Ovid Medline, Cochrane Library, and Cumulative Index to Nursing & Allied Health Literature was performed on 7 April 2023, in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines for scoping reviews. The searches were conducted using the keywords relating to "orthopedic" and "three-dimensional printing". No restrictions were placed on the date of publication.
1333 articles were included in the final synthesis of this review. 6 main themes were identified: surgical planning (57.01%), implants (28.73%), prostheses (5.03%), surgical training and education (4.20%), orthosis (3.98%) and patient education (1.05%). Specialties that commonly used 3D printing included trauma, spine, and adult reconstruction. Common anatomical sites included the pelvis, spine, and knee. Titanium was the most used material, followed by polylactic acid and resin. Titanium was predominantly used in 3D-printed implants while polylactic acid and resin were predominantly used during surgical planning. There was a paucity of literature on legal and economic papers.
Existing literature demonstrates the growing applications of 3D printing in orthopedics with the potential for it to address the needs of low-income countries, improve patient outcomes, and enhance surgical practices. However, further research is needed to explore the clinical, and economic aspects and optimization of workflow to establish 3D printing as a standard of care in orthopedics.
鉴于3D打印在临床实践中的应用日益广泛，本综述旨在提供3D打印在骨科当前应用的最新概述，并找出现有文献中的空白。
根据系统评价和Meta分析扩展综述的首选报告项目指南，于2023年4月7日对PubMed、Embase、Ovid Medline、Cochrane图书馆和护理及联合健康文献累积索引进行了电子数据库检索。使用与“骨科”和“三维打印”相关的关键词进行检索。对出版日期不设限制。
1333篇文章被纳入本综述的最终综合分析。确定了6个主要主题：手术规划（57.01%）、植入物（28.73%）、假体（5.03%）、手术培训与教育（4.20%）、矫形器（3.98%）和患者教育（1.05%）。常用3D打印的专业包括创伤、脊柱和成人重建。常见的解剖部位包括骨盆、脊柱和膝盖。钛是使用最多的材料，其次是聚乳酸和树脂。钛主要用于3D打印植入物，而聚乳酸和树脂主要用于手术规划。关于法律和经济方面的文献较少。
现有文献表明3D打印在骨科的应用越来越广泛，有可能满足低收入国家的需求、改善患者预后并提升手术实践。然而，需要进一步研究以探索临床、经济方面以及工作流程的优化，从而将3D打印确立为骨科的一种护理标准。
