Belfrage E, Enocksson E, Kalin M, Marland M
Scand J Infect Dis. 1985;17(4):413-20. doi: 10.3109/13813458509058783.
Recurrent epidemic spread of beta-hemolytic streptococci of Lancefield group A was seen in our maternity wards during a period when 70% ethanol was used for umbilical care. This prompted us to compare this regimen with one using 4% chlorhexidine in detergent for a period of 9 consecutive months. 2016 infants were studied. Umbilical colonization with group A, C and G streptococci was almost eliminated by use of 4% chlorhexidine in detergent and epidemic spread was not seen. Colonization rate of Staphylococcus aureus at the umbilical cord was reduced from 92% to 27%. The incidence of superficial infections during the first 4 postnatal weeks was reduced. Following the 9 months of comparative study 4% chlorhexidine in detergent has been routinely used in umbilical cord care at our hospital for more than 1 year without any epidemic spread of streptococci and with the same antibacterial efficiency.
在我们的产科病房，当使用70%乙醇进行脐部护理期间，曾出现过A群兰氏β溶血性链球菌的反复流行传播。这促使我们将该方案与连续9个月使用含4%洗必泰的清洁剂的方案进行比较。对2016名婴儿进行了研究。使用含4%洗必泰的清洁剂几乎消除了A、C和G群链球菌在脐部的定植，且未出现流行传播。脐带金黄色葡萄球菌的定植率从92%降至27%。产后前4周浅表感染的发生率降低。经过9个月的比较研究后，含4%洗必泰的清洁剂已在我院常规用于脐带护理1年多，未出现链球菌的任何流行传播，且抗菌效果相同。
