Chen Yuxuan, Chen Ruipeng, Wang Hui, Zhao Jiawen, Pan Dongxia, Yang Liang, Tang Xiangfang, Xiong Benhai
State Key Laboratory of Animal Nutrition and Feeding, Institute of Animal Science, Chinese Academy of Agricultural Sciences Beijing 100193 China
Nanoscale Adv. 2025 Sep 4. doi: 10.1039/d5na00394f.
Mycotoxins in feed can pose significant risks to the health of livestock and poultry, leading to reduced economic returns and impaired production efficiency, thereby impeding the sustainable development of the livestock industry. Consequently, the exploration of highly sensitive, simple and rapid detection methods for trace mycotoxins in feed is crucial for ensuring feed safety and promoting industrial sustainability. Surface-enhanced Raman spectroscopy (SERS), a rapid detection method characterized by high sensitivity, ease of operation, and resistance to water interference, has gained substantial traction in mycotoxin detection within feed matrices in recent years. This review systematically summarizes the enhancement mechanisms, substrate types, and detection technologies of SERS, with a focus on analyzing the application cases and limitations of different substrates in the detection of mycotoxins in feeds. Additionally, it explores the joint application strategies of SERS with other technologies. Future research should focus on the development of low-cost substrates, anti-interference design for complex matrices, and integration of portable devices, so as to promote SERS technology to become the core solution for on-site rapid detection of feed safety.
饲料中的霉菌毒素会对畜禽健康构成重大风险，导致经济回报降低和生产效率受损，从而阻碍畜牧业的可持续发展。因此，探索用于饲料中痕量霉菌毒素的高灵敏度、简单快速的检测方法对于确保饲料安全和促进产业可持续发展至关重要。表面增强拉曼光谱（SERS）作为一种具有高灵敏度、操作简便且抗水干扰特点的快速检测方法，近年来在饲料基质中霉菌毒素检测方面获得了广泛关注。本文系统总结了SERS的增强机制、基底类型和检测技术，重点分析了不同基底在饲料霉菌毒素检测中的应用案例及局限性。此外，还探讨了SERS与其他技术的联合应用策略。未来的研究应聚焦于低成本基底的开发、复杂基质的抗干扰设计以及便携式设备的集成，以推动SERS技术成为饲料安全现场快速检测的核心解决方案。
