Daya Sheraz, Akahoshi Takayuki, Bosc Camille, Mouchel Romain, Chassain Christophe, Van Acker Emmanuel, Di Maria Alessandra, Fogagnolo Paolo
Centre for Sight, East Grinstead, UK.
Nihonbashi Cataract-Clinic, Tokyo, Japan.
Clin Ophthalmol. 2025 Sep 2;19:3121-3131. doi: 10.2147/OPTH.S542276. eCollection 2025.
To report clinical outcomes in patients implanted with an isofocal optic-design intraocular lens (IOL) with double C-loop haptics following cataract surgery.
This was a multicentre-prospective-study involving 108 eyes (54 subjects) implanted with the Isopure Serenity (BVI, Inc). IOL. At least 3 months after the surgery, the following parameters were analysed: refraction, monocular uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), uncorrected intermediate visual acuity (UIVA) and distance corrected-intermediate visual acuity (DCIVA) both at 80 and 66 cm, uncorrected near visual acuity (UNVA), and distance corrected near visual acuity (DCNVA) at 40 cm. In addition, the binocular defocus curve was measured.
79.63% and 98.15% of eyes were within ±0.50D and ±1.00D of the target spherical equivalent, respectively. 68.41% and 98.15% of eyes had a UDVA and CDVA of 20/20 or better, respectively, with 88.89% and 99.07% achieving 20/25 or better, respectively (the mean values for UDVA and CDVA were 0.02±0.11 and -0.04±0.05 logMAR, respectively). 77.14% and 39.39% of eyes achieved a DCIVA of 20/32 or better at 80 cm and 66 cm, respectively, and 90% and 72.73% achieved a DCIVA of 20/40 or better at 80 and 66 cm, respectively (the mean values for DCIVA were 0.19±0.10 and 0.28±0.11 logMAR, 80 cm and at 66 cm, respectively). 25% and 15.15% of eyes had a UNVA and DCNVA of 20/32 or better, respectively, with 39.81% and 31.82% achieving a UNVA and DCNVA of 20/40 or better, respectively (mean values for UNVA and DCNVA were 0.37±0.15 logMAR and 0.40±0.13 logMAR, respectively). The defocus curve showed a peak of visual acuity at far distance with a depth-of-focus value of about 1.75D.
Patients implanted with the new Isopure Serenity IOL with double C-loop haptics showed good visual performance at far distance with functional intermediate vision and accurate refractive outcomes.
报告白内障手术后植入具有双C袢襻的等焦光学设计人工晶状体（IOL）患者的临床结果。
这是一项多中心前瞻性研究，涉及108只眼（54名受试者）植入了Isopure Serenity（BVI公司）IOL。术后至少3个月，分析以下参数：屈光、单眼未矫正远视力（UDVA）、矫正远视力（CDVA）、未矫正中视力（UIVA）以及80 cm和66 cm处的距离矫正中视力（DCIVA）、未矫正近视力（UNVA）以及40 cm处的距离矫正近视力（DCNVA）。此外，测量双眼散焦曲线。
分别有79.63%和98.15%的眼在目标球镜等效值的±0.50D和±1.00D范围内。分别有68.41%和98.15%的眼UDVA和CDVA为20/20或更好，分别有88.89%和99.07%的眼达到20/25或更好（UDVA和CDVA的平均值分别为0.02±0.11和 -0.04±0.05 logMAR）。分别有77.14%和39.39%的眼在80 cm和66 cm处DCIVA为20/32或更好，分别有90%和72.73%的眼在80 cm和66 cm处DCIVA为20/40或更好（80 cm和66 cm处DCIVA的平均值分别为0.19±0.10和0.28±0.11 logMAR）。分别有25%和15.15%的眼UNVA和DCNVA为20/32或更好，分别有39.81%和31.82%的眼UNVA和DCNVA为20/40或更好（UNVA和DCNVA的平均值分别为0.37±0.15 logMAR和0.40±0.13 logMAR）。散焦曲线显示远视力有一个峰值，焦深值约为1.�5D。
植入新型具有双C袢襻的Isopure Serenity IOL的患者在远视力方面表现良好，具有功能性中视力且屈光结果准确。
