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伊朗系统生物学倡议路线图。

Roadmap for a Systems Biology Initiative in Iran.

作者信息

Kamali Zoha, Jalilvandnejad Amir, Falenji Bentolhoda, Zarei Parvin, Lotfi Maryam, Hadizadeh Fatemeh, Vaez Ahmad

机构信息

Department of Bioinformatics, Isfahan University of Medical Sciences, Isfahan, Iran.

Department of Epidemiology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.

出版信息

J Med Signals Sens. 2025 Sep 1;15:26. doi: 10.4103/jmss.jmss_66_24. eCollection 2025.

Abstract

BACKGROUND

Systems biology is an interdisciplinary approach, which will fundamentally transform the way biology is perceived and studied. Subsequently, biomedical knowledge, medical practice, health systems, and related industries will be changed. This change will ultimately lay the foundation for the new generation of medicine or high-performance medicine, so-called personalized medicine. The results of this renovation are already emerging at five levels: knowledge level, patient level, therapist level, health system level, and industry level. A national roadmap is the right way to shape the future in a conscious, effective, and preconceived way.

METHODS

Here, we provide a roadmap to expand systems biology approach in Iran, which can serve as a model for other countries with similar resources and strategic situation. We begin with field studies to map the current situation in the field and potential promoters and deterrents. We then identify key players and evaluate their power and benefit from expansion of systems biology approach. Finally, we provide strategies, key action areas, and feasible actions, as well as achievable goals and realistic vision and mission in a 10-year timeline, all in light of guidance from experts and pioneers in the field of systems biology.

RESULTS

We identified the strategic position of Iran at WO area, which means the need to focus on conservative strategies to minimize the weaknesses leveraging opportunities.

CONCLUSIONS

Implementation of our suggestive 10-year roadmap will enhance the current situation of Iran in systems biology field to be the pioneer in west asia and a major player in the world.

摘要

背景

系统生物学是一种跨学科方法,它将从根本上改变生物学的认知和研究方式。随后,生物医学知识、医疗实践、卫生系统及相关产业都将发生变革。这种变革最终将为新一代医学或高性能医学,即所谓的个性化医学奠定基础。这场革新的成果已在知识层面、患者层面、治疗师层面、卫生系统层面和产业层面这五个层面显现出来。国家路线图是以有意识、有效且预先设想的方式塑造未来的正确途径。

方法

在此,我们提供一份在伊朗扩展系统生物学方法的路线图,它可为其他具有类似资源和战略形势的国家提供范例。我们首先开展实地研究,以描绘该领域的现状以及潜在的推动者和阻碍因素。然后我们确定关键参与者,并评估他们的影响力以及从系统生物学方法扩展中获得的益处。最后,我们根据系统生物学领域专家和先驱者的指导意见,在10年时间跨度内提供战略、关键行动领域、可行行动,以及可实现的目标和切实可行的愿景与使命。

结果

我们确定了伊朗在世界其他地区(WO)的战略地位,这意味着需要专注于保守战略,以利用机会最小化弱点。

结论

实施我们建议的10年路线图将提升伊朗在系统生物学领域的现状,使其成为西亚的先驱以及世界上的主要参与者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0988/12431705/fef43b8bd2f3/JMSS-15-26-g001.jpg

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