García-Calderó G, Politi S Peregalli
Institute for Biomedical Ethics (IBMB), University of Basel, Bernoullistrasse 28, 4056, Basel, Switzerland.
Child and Adolescent Psychiatry Clinical Services, Geneva University Hospital, Rue Gabrielle-Perret-Gentil 4, 1205, Geneva, Switzerland.
J Bioeth Inq. 2025 Sep 15. doi: 10.1007/s11673-025-10437-4.
Prescribing antidepressants and benzodiazepines for patients with emotional distress is a common practice in primary healthcare that raises certain ethical questions. This paper has three aims. First, to describe the motivations that lead general practitioners to prescribe antidepressants and benzodiazepines in these cases. Second, to reflect on the ethical implications of such prescriptions based on the four principles of biomedical ethics defined by Beauchamp and Childress (autonomy, nonmaleficence, beneficence, and justice). Finally, to propose some recommendations for the mitigation of the medicalization of emotional distress in primary healthcare. Results show that general practitioners seek to alleviate patients' suffering but their prescribing decisions are influenced by some uncertainties in clinical judgement as well as by systemic factors (patients' pressures, time constraints, and unawareness of resources). Ethical issues arise in relation to the potential for dependence, the questionable long-term benefit of prescriptions, the uncritical fulfillment of patients' expectations, and the impediment to address underlying social issues or to develop patients' capabilities. Clinical consultation should be founded on effective communication between doctors and patients and a holistic care approach that acknowledges the psychological, social, and existential dimensions should replace a merely symptomatic approach. Some strategies to mitigate medicalization are proposed: the promotion of regular monitoring visits with patients and multidisciplinary collaboration, the enhancement of physicians' knowledge about non-pharmacological interventions, as well as the establishment of an evidence-base for the effectiveness of these drugs in the primary healthcare setting.
在初级医疗保健中,为情绪困扰患者开抗抑郁药和苯二氮䓬类药物是一种常见做法,但这引发了一些伦理问题。本文有三个目标。第一,描述导致全科医生在这些情况下开具抗抑郁药和苯二氮䓬类药物的动机。第二,基于博尚和奇尔德雷斯定义的生物医学伦理四原则(自主、不伤害、有益和公正),反思此类处方的伦理含义。最后,提出一些建议,以减轻初级医疗保健中情绪困扰的医学化。结果表明,全科医生试图减轻患者的痛苦,但其开药决定受到临床判断中的一些不确定性以及系统因素(患者压力、时间限制和资源意识不足)的影响。在药物依赖可能性、处方的长期益处存疑、不加批判地满足患者期望以及解决潜在社会问题或培养患者能力方面存在障碍等问题上,伦理问题随之产生。临床咨询应建立在医生与患者有效沟通的基础上,一种承认心理、社会和生存维度的整体护理方法应取代仅仅是对症治疗的方法。提出了一些减轻医学化的策略:促进对患者的定期监测访视和多学科协作,增强医生对非药物干预的知识,以及建立这些药物在初级医疗保健环境中有效性的证据基础。