Jain Manoj, Singh Anurag, Kumar Nirbhay, Mohindra Samir
Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, IND.
Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, IND.
Cureus. 2025 Aug 15;17(8):e90158. doi: 10.7759/cureus.90158. eCollection 2025 Aug.
Pancreatic metastasis from renal cell carcinoma (RCC) is a rare and often delayed event, frequently resembling primary pancreatic neoplasms such as neuroendocrine tumors, which poses substantial diagnostic challenges. This report describes a case involving a 74-year-old male patient with pancreatic metastasis originating from the left kidney. Seven years earlier, the patient had undergone a left nephrectomy for RCC. Follow-up evaluations after seven years revealed a mass in the pancreatic body, with initial radiological assessments suggesting a provisional diagnosis of a neuroendocrine tumor. Endoscopic ultrasound-guided fine-needle biopsy of the pancreatic lesion, combined with a panel of immunohistochemistry markers, confirmed that the mass was metastatic RCC. A surgical procedure is planned for the patient. This case report presents an uncommon instance of delayed pancreatic metastasis from RCC and reviews the relevant literature on its clinical presentation, diagnostic approaches, and treatment options.
肾细胞癌（RCC）的胰腺转移是一种罕见且常出现延迟的情况，常类似于原发性胰腺肿瘤，如神经内分泌肿瘤，这带来了重大的诊断挑战。本报告描述了一例涉及一名74岁男性患者的病例，该患者发生了源自左肾的胰腺转移。七年前，该患者因RCC接受了左肾切除术。七年后的随访评估发现胰体有一个肿块，最初的放射学评估提示初步诊断为神经内分泌肿瘤。对胰腺病变进行内镜超声引导下细针穿刺活检，并结合一组免疫组化标志物，证实该肿块为转移性RCC。已为该患者制定了手术方案。本病例报告呈现了RCC延迟性胰腺转移的一个罕见实例，并综述了其临床表现、诊断方法和治疗选择的相关文献。
