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良性输尿管狭窄微创重建术后的临床结局及健康相关生活质量评估

Clinical outcomes and health-related quality of life assessment following minimally invasive reconstructive surgery for benign ureteral strictures.

作者信息

Zhang Quan, Wang Hanqing, Zhang Xuemeng, Gao Zhenhua, Li Hao, Zhang Baiyu

机构信息

Department of Urology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China.

出版信息

World J Urol. 2025 Sep 17;43(1):558. doi: 10.1007/s00345-025-05926-5.

Abstract

BACKGROUND

To evaluate the clinical efficacy of minimally invasive ureteral reconstruction for benign strictures and analyze its impact on health-related quality of life (HRQoL) and psychological status.

METHODS

This retrospective study included 29 patients undergoing robotic/laparoscopic ureteral reconstruction at our institution. Surgical outcomes were assessed through imaging, laboratory parameters, and patient-reported outcomes assessed via the validated SF-36 quality-of-life instrument and Hospital Anxiety and Depression Scale (HADS) psychological distress screening tool.

RESULTS

With a median follow-up of 12 months, the surgical success rate was 96.6%. The perioperative complication rate was 6.90% (2 cases of transient high fever), with no severe adverse events observed. Preoperative SF-36 scores in physical functioning (PF) and bodily pain (BP) domains were significantly lower than those of the general population (p < 0.001). Postoperatively, except for vitality(VT) and mental health (MH) domains which surpassed population norms, scores in other dimensions showed no significant differences compared to the general population (p > 0.05). Notably, all SF-36 domains demonstrated significant improvement from baseline (p < 0.05). Additionally, both anxiety and depression scores assessed by HADS decreased markedly after surgery (p < 0.05).

CONCLUSION

Minimally invasive ureteral repair and reconstruction effectively relieves obstruction, improves renal function, and significantly enhances health-related quality of life and psychological well-being, representing a safe therapeutic option for benign ureteral strictures. Surgical intervention reduces the need for long-term stent or nephrostomy placement, thereby alleviating physical and psychological burdens. Further studies with expanded cohorts and extended follow-up durations are warranted to validate long-term outcomes.

摘要

背景

评估微创输尿管重建术治疗良性狭窄的临床疗效,并分析其对健康相关生活质量(HRQoL)和心理状态的影响。

方法

这项回顾性研究纳入了在本机构接受机器人/腹腔镜输尿管重建术的29例患者。通过影像学、实验室参数以及使用经过验证的SF-36生活质量量表和医院焦虑抑郁量表(HADS)心理困扰筛查工具评估患者报告的结果来评估手术效果。

结果

中位随访时间为12个月,手术成功率为96.6%。围手术期并发症发生率为6.90%(2例短暂高热),未观察到严重不良事件。术前SF-36身体功能(PF)和身体疼痛(BP)领域的得分显著低于一般人群(p < 0.001)。术后,除活力(VT)和心理健康(MH)领域超过人群规范外,其他维度的得分与一般人群相比无显著差异(p > 0.05)。值得注意的是,所有SF-36领域与基线相比均有显著改善(p < 0.05)。此外,HADS评估的焦虑和抑郁得分在术后均显著下降(p < 0.05)。

结论

微创输尿管修复重建术能有效缓解梗阻,改善肾功能,并显著提高健康相关生活质量和心理健康水平,是良性输尿管狭窄的一种安全治疗选择。手术干预减少了长期放置支架或肾造瘘的需求,从而减轻了身体和心理负担。有必要进行更大样本量和更长随访时间的进一步研究以验证长期疗效。

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