Donin Angela S, Limb Elizabeth, Tang Jonathan C Y, Whincup Peter H
Population Health Research Institute, City St George's, University of Londonhttps://ror.org/047ybhc09, London, UK.
University of East Anglia, Faculty of Medicine and Health Sciences, Norwich, UK.
Br J Nutr. 2025 Sep 23:1-7. doi: 10.1017/S0007114525105187.
Vitamin D deficiency is common in the UK, especially in certain ethnic minority populations. There is limited information on childhood vitamin D status in the UK, or factors associated with vitamin D deficiency. Using a cross-sectional study of 4650 children of South Asian, Black African and Caribbean and White European origins (9-10 years old) surveyed between 2004 and 2007, we investigated measurements of circulating 25(OH)D concentrations (a measure of vitamin D status) and anthropometric measurements. Overall, 68 % of children had 25(OH)D concentrations ≤ 50 nmol/L and were either insufficient (25-50 nmol/L) (45 %) or deficient (< 25 nmol/L) (23 %). Mean 25(OH)D concentrations were lowest in South Asian (especially Bangladeshi) children, intermediate in Black African and Caribbean and highest in White European children. Mean values were ≤ 50 nmol/L for all children during the winter months and ≤ 50 nmol/L throughout the year for South Asian, Black African and Caribbean children. In analyses adjusted for season, age, sex, ethnicity, socio-economic status and fat mass index, girls had a higher risk of being vitamin D deficient or insufficient (OR 1·49, 95 % CI 1·32, 1·68) compared with boys. South Asian children (OR 25·49, 95 % CI 19·95, 32·57) and Black African and Caribbean children (OR 10·31, 95 % CI 10·31, 17·52) had the highest risks of being deficient or insufficient compared with White European children. Childhood vitamin D deficiency was common in this study population. In the UK, targeted and novel interventions are needed to increase 25(OH)D concentrations, particularly South Asian and Black African and Caribbean children and reduce the health risks associated with low vitamin D status.
维生素D缺乏在英国很常见，尤其是在某些少数族裔人群中。关于英国儿童维生素D状况或与维生素D缺乏相关因素的信息有限。我们利用2004年至2007年间对4650名南亚、非洲裔加勒比和欧洲裔白人儿童（9至10岁）进行的横断面研究，调查了循环25(OH)D浓度（维生素D状况的一项指标）测量值和人体测量数据。总体而言，68%的儿童25(OH)D浓度≤50 nmol/L，处于不足（25至50 nmol/L）（45%）或缺乏（<25 nmol/L）（23%）状态。南亚（尤其是孟加拉裔）儿童的平均25(OH)D浓度最低，非洲裔加勒比儿童居中，欧洲裔白人儿童最高。在冬季，所有儿童的平均值均≤50 nmol/L，而南亚、非洲裔加勒比儿童全年的平均值均≤50 nmol/L。在对季节、年龄、性别、种族、社会经济地位和脂肪质量指数进行校正的分析中，与男孩相比，女孩维生素D缺乏或不足的风险更高（比值比1.49，95%置信区间1.32，1.68）。与欧洲裔白人儿童相比，南亚儿童（比值比25.49，95%置信区间19.95，32.57）以及非洲裔加勒比儿童（比值比10.31，95%置信区间10.31，17.52）缺乏或不足的风险最高。在该研究人群中，儿童维生素D缺乏很常见。在英国，需要有针对性的新型干预措施来提高25(OH)D浓度，尤其是南亚和非洲裔加勒比儿童，并降低与低维生素D状态相关的健康风险。
