Azócar-Aedo Lucía, Meniconi Gloria, Pino-Olguín Carolina, Gallardo María
Facultad de Medicina Veterinaria, Escuela de Medicina Veterinaria, Universidad San Sebastián, Sede de la Patagonia, Puerto Montt 5480000, Chile.
Facultad de Medicina y Ciencias de la Salud, Escuela de Medicina Veterinaria, Universidad Mayor, Campus Huechuraba, Santiago 8580000, Chile.
Trop Med Infect Dis. 2025 Sep 3;10(9):253. doi: 10.3390/tropicalmed10090253.
At a veterinary hospital in southern Chile, we conducted an epidemiological study involving domestic dogs, cats, and horses to determine the seropositivity for pathogenic spp., identify the infecting serogroups, measure antibody titers, and characterize seropositive animals by sex and age. None of the sampled animals showed clinical signs of leptospirosis. The microscopic agglutination test, using a panel of eight serogroups, was used for diagnosis. The seropositivity was 36.5% (95% confidence interval [CI] = 24.5-48.4) in dogs, 12.9% (95% CI = 2.6-23.1) in cats, and 45.2% (95% CI = 30.1-60.2) in horses. Serological reactions were detected for the Tarassovi and Canicola serogroups in dogs, Sejroe, Canicola, Icterohaemorrhagiae, and Grippotyphosa in horses, and Tarassovi in cats. The most frequent antibody titers were 1:200 and 1:400 in dogs, 1:400 in cats, and 1:800 in horses. The distribution of seropositivity varied by sex and age across different animal species. The seropositivity for pathogenic in dogs, cats, and horses attending a veterinary hospital underscores the role of domestic animals as sentinels for zoonotic diseases. This finding has implications for epidemiological surveillance systems in increasing awareness of seropositivity and establishing specific prevention measures to mitigate the risk of leptospirosis transmission.
在智利南部的一家兽医医院，我们对家犬、猫和马进行了一项流行病学研究，以确定致病性钩端螺旋体血清阳性率，识别感染血清群，测量抗体滴度，并按性别和年龄对血清阳性动物进行特征分析。所有采样动物均未表现出钩端螺旋体病的临床症状。采用一组八个血清群的显微镜凝集试验进行诊断。犬的血清阳性率为36.5%（95%置信区间[CI]=24.5-48.4），猫为12.9%（95%CI=2.6-23.1），马为45.2%（95%CI=30.1-60.2）。在犬中检测到针对塔拉索夫血清群和犬血清群的血清学反应，马中检测到 sejroe、犬血清群、出血性黄疸型和波摩那群，猫中检测到塔拉索夫血清群。犬中最常见的抗体滴度为1:200和1:400，猫为1:400，马为1:800。不同动物物种的血清阳性率分布因性别和年龄而异。在一家兽医医院就诊的犬、猫和马的致病性钩端螺旋体血清阳性率凸显了家畜作为人畜共患病哨兵的作用。这一发现对流行病学监测系统具有重要意义，有助于提高对血清阳性率的认识，并制定具体的预防措施以降低钩端螺旋体病传播风险。
