荧光素标记的抗人 IgM 结合物的免疫特异性评估。
Evaluation of the immunological specificity of fluorescein-labelled anti-human IgM conjugates.
作者信息
Chantler S, Haire M
出版信息
Immunology. 1972 Jul;23(1):7-12.
Abstract
The immunological specificity of two anti-IgM fluorescein-labelled antisera was evaluated in gel diffusion, by the direct immunofluorescent technique on characterized bone marrow preparations taken from patients with myeloma and by an indirect staining method employing virus-infected cells and selected post-infection sera. The results show that neither gel diffusion nor direct immunofluorescent methods provide a reliable index of specificity for conjugates to be used in indirect procedures.
摘要
通过凝胶扩散法、对取自骨髓瘤患者的特征性骨髓制剂采用直接免疫荧光技术以及采用病毒感染细胞和选定的感染后血清的间接染色法，对两种抗IgM荧光素标记抗血清的免疫特异性进行了评估。结果表明，凝胶扩散法和直接免疫荧光法均不能为间接程序中使用的结合物提供可靠的特异性指标。
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Structure of antibody molecules.抗体分子的结构。
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