多发性硬化症及其他神经系统疾病中淋巴细胞对脑碱性蛋白的致敏作用。
Lymphocyte sensitization to basic protein of brain in multiple sclerosis and other neurological diseases.
作者信息
Caspary E A, Field E J
出版信息
J Neurol Neurosurg Psychiatry. 1974 Jun;37(6):701-3. doi: 10.1136/jnnp.37.6.701.
Abstract
The number of lymphocytes in the blood sensitized to encephalitogenic factor (EF) is less in multiple sclerosis than it is in general paralysis of the insane. The number appears related to the extent of parenchymatous destruction. The study offers no support for the view that lymphocyte sensitization to EF is of pathogenetic significance in multiple sclerosis.
摘要
在多发性硬化症中，血液中对致脑炎因子（EF）致敏的淋巴细胞数量比在精神错乱性全身麻痹中要少。该数量似乎与实质破坏的程度有关。这项研究并不支持淋巴细胞对EF的致敏在多发性硬化症中具有致病意义这一观点。
相似文献
1
Lymphocyte sensitization to basic protein of brain in multiple sclerosis and other neurological diseases.多发性硬化症及其他神经系统疾病中淋巴细胞对脑碱性蛋白的致敏作用。
J Neurol Neurosurg Psychiatry. 1974 Jun;37(6):701-3. doi: 10.1136/jnnp.37.6.701.
2
Lymphocyte sensitization to thymus and lymph node antigen in multiple sclerosis and other neurological diseases.多发性硬化症及其他神经系统疾病中淋巴细胞对胸腺和淋巴结抗原的致敏作用。
J Neurol Neurosurg Psychiatry. 1973 Aug;36(4):604-6. doi: 10.1136/jnnp.36.4.604.
3
Sensitization of cerebrospinal fluid and peripheral blood lymphocytes to myelin basic protein in multiple sclerosis.多发性硬化症中脑脊液和外周血淋巴细胞对髓鞘碱性蛋白的致敏作用。
Acta Neurol Scand. 1982 Jul;66(1):121-9. doi: 10.1111/j.1600-0404.1982.tb03136.x.
4
Lymphocytes sensitised to basic encephalitogen in patients with multiple sclerosis unresponsive to steroid therapy.
Lancet. 1974 Jul 13;2(7872):66-9. doi: 10.1016/s0140-6736(74)91633-x.
5
Lymphocyte transformation in the presence of myelin basic protein in multiple sclerosis and control subjects.多发性硬化症患者及对照受试者在髓鞘碱性蛋白存在下的淋巴细胞转化
Acta Neurol Scand. 1979 Aug;60(2):65-76. doi: 10.1111/j.1600-0404.1979.tb02953.x.
6
Lymphocyte sensitization to carcinoembryonic antigen (Gold) with special reference to multiple sclerosis.淋巴细胞对癌胚抗原（戈尔德）的致敏作用，特别提及多发性硬化症。
Br Med J. 1972 Nov 4;4(5835):261-3. doi: 10.1136/bmj.4.5835.261.
7
Studies of cellular sensitization to myelin antigens in multiple sclerosis. Dissociation of MIF and LBT production in response to a peptide encephalitogenic in rhesus monkeys.多发性硬化中细胞对髓鞘抗原致敏作用的研究。恒河猴对致脑炎性肽产生反应时巨噬细胞移动抑制因子（MIF）和淋巴细胞转化试验（LBT）结果的分离。
J Neurol Sci. 1977 Aug;33(1-2):111-29. doi: 10.1016/0022-510x(77)90186-1.
8
Hyperreactivity to myelin basic protein in multiple sclerosis.
J Neurol Sci. 1981 Nov-Dec;52(2-3):385-90. doi: 10.1016/0022-510x(81)90019-8.
9
Peptides of myelin basic protein stimulate T lymphocytes from patients with multiple sclerosis.
J Neuroimmunol. 1989 Mar;22(1):23-30. doi: 10.1016/0165-5728(89)90005-2.
10
Specificity of antibody-dependent lymphocyte cytotoxicity against cerebral tissue constituents in multiple sclerosis. Studies with basic protein of myelin, encephalitogenic peptide, cerebrosides and gangliosides.多发性硬化中针对脑组织成分的抗体依赖性淋巴细胞细胞毒性的特异性。对髓鞘碱性蛋白、致脑炎肽、脑苷脂和神经节苷脂的研究。
Acta Neurol Scand. 1982 Jan;65(1):30-7. doi: 10.1111/j.1600-0404.1982.tb03058.x.
引用本文的文献
1
Scrapie: a review of its relation to human disease and ageing.羊瘙痒病：关于其与人类疾病和衰老关系的综述
J Med Genet. 1976 Dec;13(6):479-95. doi: 10.1136/jmg.13.6.479.
2
Biochemical findings in multiple sclerosis. V. Transformation of lymphocytes from patients with multiple sclerosis by human basic protein.
J Neurol. 1977 Oct 7;216(3):197-205. doi: 10.1007/BF00313621.
本文引用的文献
1
AN ENCEPHALITOGENIC PROTEIN OF HUMAN ORIGIN: SOME CHEMICAL AND BIOLOGICAL PROPERTIES.一种人类源致脑炎蛋白：一些化学和生物学特性
Ann N Y Acad Sci. 1965 Mar 31;122:182-98. doi: 10.1111/j.1749-6632.1965.tb20202.x.
2
Response of human blood lymphocytes to tuberculin PPD in tissue culture.人血淋巴细胞在组织培养中对结核菌素纯蛋白衍生物的反应。
Immunology. 1967 Apr;12(4):417-29.
3
Demonstration of sensitized lymphocytes in blood.血液中致敏淋巴细胞的检测
J Clin Pathol. 1971 Mar;24(2):179-81. doi: 10.1136/jcp.24.2.179.
4
Sensitization of blood lymphocytes to possible antigens in neurological disease.血液淋巴细胞对神经疾病中可能的抗原的致敏作用。
Eur Neurol. 1970;4(5):257-66. doi: 10.1159/000114027.
5
Lymphocyte transformation in vitro measured by tritiated thymidine uptake. I. Lymphocyte culture techniques.通过氚标记胸腺嘧啶核苷摄取法体外测定淋巴细胞转化。I. 淋巴细胞培养技术。
Int Arch Allergy Appl Immunol. 1970;37(5):506-31. doi: 10.1159/000230240.
6
The macrophage electrophoretic migration (MEM) test for lymphocyte sensitization. A study of the kinetics.用于淋巴细胞致敏的巨噬细胞电泳迁移（MEM）试验。动力学研究。
Clin Exp Immunol. 1973 May;14(1):37-45.
7
Specific lymphocyte sensitization in cancer: is there a common antigen in human malignant neoplasia?癌症中的特异性淋巴细胞致敏：人类恶性肿瘤中是否存在共同抗原？
Br Med J. 1971 Jun 12;2(5762):613-7. doi: 10.1136/bmj.2.5762.613.
8
Lymphocyte sensitisation: an in-vitro test for cancer?淋巴细胞致敏：一种癌症的体外检测方法？
Lancet. 1970 Dec 26;2(7687):1337-41. doi: 10.1016/s0140-6736(70)92361-5.
Zotero 插件