甲氰咪胺对豚鼠离体灌注肺循环的某些作用。
Some effects of burimamide on the isolated perfused pulmonary circulation of the guinea-pig.
作者信息
Goadby P S, Phillip E A
出版信息
Br J Pharmacol. 1973 Oct;49(2):368-9. doi: 10.1111/j.1476-5381.1973.tb08386.x.
Abstract
Infusions of burimamide were found to potentiate the pressor response to histamine and abolish the depressor response to histamine in the presence of mepyramine, in the isolated perfused guinea-pig pulmonary circulation. It is concluded that the depressor response to histamine is due to stimulation of histamine H(2)-receptors in the pulmonary vessels.
摘要
在离体灌注的豚鼠肺循环中发现，注射布立马胺可增强对组胺的升压反应，并在存在美吡拉敏的情况下消除对组胺的降压反应。由此得出结论，对组胺的降压反应是由于肺血管中组胺H(2)受体受到刺激所致。
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