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人血清C'1酯酶抑制剂：与α-2-神经氨酸糖蛋白相同。

Human serum inhibitor of C'1 esterase: identity with alpha-2-neuraminoglycoprotein.

作者信息

Pensky J, Schwick H G

出版信息

Science. 1969 Feb 14;163(3868):698-9. doi: 10.1126/science.163.3868.698.

DOI:10.1126/science.163.3868.698
PMID:4178712
Abstract

A comparison of highly purified C'1 esterase inhibitor from human serum and alpha(2)-neuraminoglycoprotein from human plasma by immunofusion, immuneelectrophoresis, and discgel electrophoresis showed them to be antigenically identical.

摘要

通过免疫融合、免疫电泳和圆盘凝胶电泳对人血清中高度纯化的C'1酯酶抑制剂与人血浆中的α(2)-神经氨酸糖蛋白进行比较，结果表明它们在抗原性上是相同的。

相似文献

1
Human serum inhibitor of C'1 esterase: identity with alpha-2-neuraminoglycoprotein.人血清C'1酯酶抑制剂：与α-2-神经氨酸糖蛋白相同。
Science. 1969 Feb 14;163(3868):698-9. doi: 10.1126/science.163.3868.698.
2
The inhibition of plasmin, plasma kallikrein, plasma permeability factor, and the C'1r subcomponent of the first component of complement by serum C'1 esterase inhibitor.血清C'1酯酶抑制剂对纤溶酶、血浆激肽释放酶、血浆通透因子及补体第一成分的C'1r亚成分的抑制作用。
J Exp Med. 1969 Feb 1;129(2):315-31. doi: 10.1084/jem.129.2.315.
3
STUDIES ON HUMAN C'1-ESTERASE. III. EFFECT OF RABBIT ANTI-C'1-ESTERASE ON ENZYMATIC AND COMPLEMENT ACTIVITIES.人C1酯酶的研究。III.兔抗C1酯酶对酶活性和补体活性的影响。
J Immunol. 1964 Mar;92:479-90.
4
Genetically determined heterogeneity of the C1 esterase inhibitor in patients with hereditary angioneurotic edema.遗传性血管性水肿患者中C1酯酶抑制剂的基因决定异质性。
J Clin Invest. 1971 Oct;50(10):2143-9. doi: 10.1172/JCI106708.
5
Studies on purified C'1 esterase and hereditary angioneurotic oedema sera by combined electrophoresis and immune haemolysis.通过联合电泳和免疫溶血法对纯化的C'1酯酶和遗传性血管性水肿血清进行的研究。
Acta Pathol Microbiol Scand. 1965;65(3):413-20. doi: 10.1111/apm.1965.65.3.413.
6
C'1 ESTERASE EFFECT ON ACTIVITY AND PHYSICOCHEMICAL PROPERTIES OF THE FOURTH COMPONENT OF COMPLEMENT.C1酯酶对补体第四成分活性及理化性质的影响
J Exp Med. 1965 May 1;121(5):819-33. doi: 10.1084/jem.121.5.819.
7
Development of gamma G, gamma A, gamma M, beta IC-beta IA, C 1 esterase inhibitor, ceruloplasmin, transferrin, hemopexin, haptoglobin, fibrinogen, plasminogen, alpha 1-antitrypsin, orosomucoid, beta-lipoprotein, alpha 2-macroglobulin, and prealbumin in the human conceptus.人类胚胎中γG、γA、γM、βIC-βIA、C1酯酶抑制剂、铜蓝蛋白、转铁蛋白、血红素结合蛋白、触珠蛋白、纤维蛋白原、纤溶酶原、α1-抗胰蛋白酶、类粘蛋白、β-脂蛋白、α2-巨球蛋白和前白蛋白的发育情况。
J Clin Invest. 1969 Aug;48(8):1433-46. doi: 10.1172/JCI106109.
8
Mechanisms of activation of C'1 esterase in hereditary angioneurotic edema plasma in vitro.遗传性血管性水肿血浆中补体C1酯酶体外激活机制
J Exp Med. 1968 Mar 1;127(3):411-29. doi: 10.1084/jem.127.3.411.
9
The conversion of C'IS to C'1 esterase by plasmin and trypsin.纤溶酶和胰蛋白酶将C'IS转化为C'1酯酶。
J Exp Med. 1967 Feb 1;125(2):337-58. doi: 10.1084/jem.125.2.337.
10
The second component of human complement: its isolation, fragmentation by C'1 esterase, and incorporation into C'3 convertase.人补体的第二个成分：其分离、被C'1酯酶裂解以及并入C'3转化酶。
J Exp Med. 1968 Sep 1;128(3):533-51. doi: 10.1084/jem.128.3.533.

引用本文的文献

1
Potentiation of C1 esterase inhibitor by StcE, a metalloprotease secreted by Escherichia coli O157:H7.大肠杆菌O157:H7分泌的金属蛋白酶StcE对C1酯酶抑制剂的增强作用。
J Exp Med. 2004 Apr 19;199(8):1077-87. doi: 10.1084/jem.20030255.
2
The C1 esterase inhibitor and hereditary angioedema.C1酯酶抑制剂与遗传性血管性水肿
J Clin Immunol. 1982 Apr;2(2):65-8. doi: 10.1007/BF00916888.
3
Hereditary angio-oedema.遗传性血管性水肿
Proc R Soc Med. 1970 Mar;63(3):281-2. doi: 10.1177/003591577006300325.
4
The serologic behaviour of neuraminidase-treated lymphoid cells. Alloantigenicity and complement sensitivity.神经氨酸酶处理的淋巴细胞的血清学行为。同种抗原性和补体敏感性。
Clin Exp Immunol. 1972 Jul;11(3):441-60.
5
[The C1-inactivator of guinea pig serum: titration, purification and characterization of the inactivator].[豚鼠血清的C1灭活剂：灭活剂的滴定、纯化及特性鉴定]
Z Med Mikrobiol Immunol. 1971;156(2):194-207.
6
Two complement inhibitors in mouse sera.小鼠血清中的两种补体抑制剂。
Med Microbiol Immunol. 1973 Mar 8;158(3):171-5. doi: 10.1007/BF02120552.
7
Comparative effect of viral and bacterial neuraminidase on the complement sensitivity of lymphoid cells.病毒和细菌神经氨酸酶对淋巴细胞补体敏感性的比较作用
Clin Exp Immunol. 1972 Jan;10(1):139-50.
8
C1 inactivator inhibition by plasmin.纤溶酶对C1灭活剂的抑制作用。
J Clin Invest. 1970 Mar;49(3):568-75. doi: 10.1172/JCI106267.
9
Inhibitors of kallikrein in human plasma.人血浆中激肽释放酶的抑制剂
J Clin Invest. 1972 Jul;51(7):1611-23. doi: 10.1172/jci106962.
10
Genetically determined heterogeneity of the C1 esterase inhibitor in patients with hereditary angioneurotic edema.遗传性血管性水肿患者中C1酯酶抑制剂的基因决定异质性。
J Clin Invest. 1971 Oct;50(10):2143-9. doi: 10.1172/JCI106708.