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与枯草芽孢杆菌孢子形成起始相关的腺嘌呤核苷酸变化。

Adenine nucleotide changes associated with the initiation of sporulation in Bacillus subtilis.

作者信息

Hutchison K W, Hanson R S

出版信息

J Bacteriol. 1974 Jul;119(1):70-5. doi: 10.1128/jb.119.1.70-75.1974.

DOI:10.1128/jb.119.1.70-75.1974
PMID:4209776
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC245574/
Abstract

At the end of the exponential growth phase of Bacillus subtilis, there is a decrease in the energy level of the cell, whether expressed as adenosine triphosphate concentration or adenylate energy charge. Phosphate limitation of exponentially growing cells produces a similar decrease in the energy level of the cell, and sporulation is derepressed in the presence of 10 mM glucose. A reduction in the tryptophan concentration of the medium during phosphate limitation of the tryptophan auxotroph B. subtilis 168 prevented the decrease in energy charge. Cells do not sporulate under these conditions. Energy charge values of 0.30 to 0.35 found during sporulation do not lead to cell death.

摘要

在枯草芽孢杆菌指数生长阶段结束时,无论以三磷酸腺苷浓度还是腺苷酸能荷来表示,细胞的能量水平都会下降。指数生长细胞的磷酸盐限制会使细胞能量水平出现类似下降,并且在存在10 mM葡萄糖的情况下孢子形成会去阻遏。在色氨酸营养缺陷型枯草芽孢杆菌168的磷酸盐限制期间,培养基中色氨酸浓度的降低可防止能荷下降。细胞在这些条件下不会形成孢子。在孢子形成期间发现的0.30至0.35的能荷值不会导致细胞死亡。

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本文引用的文献

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Catabolite repression.分解代谢物阻遏
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