Gudding R
Acta Vet Scand. 1974;15(3):366-80. doi: 10.1186/BF03547465.
GUDDING, ROAR: Acta vet. scand. 1974, , 366–380. — The content of p-aminobenzoic acid and folic acid has been determined in some media and peptones, and the sensitivity of Bacillus megaterium, cultivated on these substrates, towards sulfonamides has been examined. The concentrations of p-aminobenzoic acid and folic acid should be as low as possible in suitable substrates, but other factors are also of importance. The presence of antagonists towards folic acid has been demonstrated in some media, and the consequences of these inhibitors are discussed. Three of the media (Paper Disc Method-Antibiotic Sensitivity Medium, AB Biodisk; Sulphonamide Antagonist Free Medium, Mast Laboratories; and Mueller Hinton, Difco Laboratories) seem to be satisfactory for the determination of the resistance of bacteria towards sulfonamides. The application of Acetobacter medium is suggested for the detection of rest concentrations of sulfonamides in foodstuffs. detection of sulfonamide residues; p-aminobenzoic acid; folic acid.
古丁，罗尔：《兽医学报》1974年，第 366 - 380 页。——已测定了某些培养基和蛋白胨中对氨基苯甲酸和叶酸的含量，并检测了在这些底物上培养的巨大芽孢杆菌对磺胺类药物的敏感性。在合适的底物中，对氨基苯甲酸和叶酸的浓度应尽可能低，但其他因素也很重要。已在某些培养基中证实存在叶酸拮抗剂，并讨论了这些抑制剂的影响。其中三种培养基（纸片法 - 抗生素敏感性培养基，AB 生物盘；无磺胺拮抗剂培养基，Mast 实验室；以及穆勒 - 欣顿培养基，Difco 实验室）似乎对于测定细菌对磺胺类药物的耐药性是令人满意的。建议应用醋酸杆菌培养基来检测食品中磺胺类药物的残留浓度。磺胺类药物残留的检测；对氨基苯甲酸；叶酸。
