Ulstein M, Sagen N, Eikhom S N
Int J Gynaecol Obstet. 1979 Nov-Dec;17(3):243-5. doi: 10.1002/j.1879-3479.1979.tb00158.x.
A comparative study of the efficacy of oral prostaglandin E2 and buccal tablets of demoxytocin for induction of labor in overdue pregnancies was made in groups of randomly selected patients. Labor was successfully induced in 95.7% of the women in the prostaglandin group and 92.1% of the women in the demoxytocin group. Although the operative delivery rate was low in both groups, it was significantly higher for the demoxytocin group. A low rate of perinatal distress was recorded and there were no serious side effects in either group. The time from start of induction until delivery, as well as the time from amniotomy until delivery, were compared for primiparae and multiparae separately. No significant differences were found. The blood loss during the third stage of labor was lower in the prostaglandin group. We find oral induction of labor in overdue pregnancies effective, safe and convenient.
对随机选取的过期妊娠患者分组进行口服前列腺素E2和地莫前列醇含片引产效果的比较研究。前列腺素组95.7%的女性引产成功，地莫前列醇组为92.1%。虽然两组的手术分娩率都较低，但地莫前列醇组显著更高。围产期窘迫发生率较低，两组均无严重副作用。分别对初产妇和经产妇从引产开始至分娩的时间以及从破膜至分娩的时间进行了比较，未发现显著差异。前列腺素组第三产程的失血量较少。我们发现过期妊娠口服引产有效、安全且方便。
