主动Arthus反应中对血小板的需求。
The requirement for platelets in the active Arthus reaction.
作者信息
Margaretten W, McKay D G
出版信息
Am J Pathol. 1971 Aug;64(2):257-70.
Abstract
The active Arthus reaction was completely inhibited in rabbits made thrombocytopenic with platelet antiserum. Platelets or some platelet factor is necessary for the development of immune vasculitis in this model. Since the classic Arthus reaction depends on the union of extravascular antigen with intravascular antibody, it is probable that the missing platelet factor is an agent that alters vascular permeability.
摘要
用血小板抗血清使家兔发生血小板减少后，主动阿图斯反应被完全抑制。在该模型中，血小板或某些血小板因子对于免疫性血管炎的发生是必需的。由于经典的阿图斯反应依赖于血管外抗原与血管内抗体的结合，缺失的血小板因子很可能是一种改变血管通透性的因子。
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