氨苄西林皮疹的前瞻性研究。协作研究小组报告。
Prospective study of ampicillin rash. Report of a collaborative study group.
出版信息
Br Med J. 1973 Jan 6;1(5844):7-9.
Abstract
A multicentre prospective study of 933 patients being treated with ampicillin showed a rash incidence of 7.3%. The rash was commonest in women and patients suffering from viral infections. Most rashes were maculopapular and were not associated with features of true penicillin allergy. We conclude that the development of a maculopapular rash during or after treatment with ampicillin is not in itself a contraindication to future treatment with the penicillins.
摘要
一项针对933名接受氨苄西林治疗患者的多中心前瞻性研究显示，皮疹发生率为7.3%。皮疹在女性和病毒感染患者中最为常见。大多数皮疹为斑丘疹，与真正的青霉素过敏特征无关。我们得出结论，在氨苄西林治疗期间或之后出现斑丘疹本身并非未来使用青霉素治疗的禁忌证。
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