乳糜泻发病率的下降
Decreasing incidence of coeliac disease.
作者信息
Stevens F M, Egan-Mitchell B, Cryan E, McCarthy C F, McNicholl B
出版信息
Arch Dis Child. 1987 May;62(5):465-8. doi: 10.1136/adc.62.5.465.
Abstract
Between 1960 and 1974 the incidence of coeliac disease in children under 12 years in County Galway remained fairly constant, but since 1975 it has fallen by 62% and the lowered incidence seems well established. The number of those who were breast fed and the age at which first gluten feeding took place during the 22 years both increased significantly and from the mid-70s total protein content and osmolarity of proprietary cow's milk formulas were reduced. All three factors may be relevant. A negative correlation with the incidence of gastroenteritis was found.
摘要
1960年至1974年间，戈尔韦郡12岁以下儿童的乳糜泻发病率保持相当稳定，但自1975年以来已下降了62%，且发病率降低的情况似乎已得到充分证实。在这22年中，母乳喂养的人数以及首次摄入麸质的年龄均显著增加，并且从70年代中期开始，市售牛奶配方奶粉的总蛋白含量和渗透压都有所降低。所有这三个因素可能都与之相关。研究发现，这与肠胃炎的发病率呈负相关。
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