用烟酰胺腺嘌呤二核苷酸连接的脱氢酶替代磷酸烯醇丙酮酸依赖性磷酸转移酶以利用甘露醇。
Replacement of a phosphoenolpyruvate-dependent phosphotransferase by a nicotinamide adenine dinucleotide-linked dehydrogenase for the utilization of mannitol.
作者信息
Tanaka S, Lerner S A, Lin E C
出版信息
J Bacteriol. 1967 Feb;93(2):642-8. doi: 10.1128/jb.93.2.642-648.1967.
Abstract
Mannitol is dissimilated by Aerobacter aerogenes via an inducible pathway initiated by a phosphotransferase system dependent upon phosphoenolpyruvate as the phosphoryl donor. A mutational block in this pathway can be suppressed either at the phenotypic level by induction of d-arabitol dehydrogenase, an enzyme fortuitously capable of converting mannitol to fructose, or genotypically by a constitutive mutation in the d-arabitol system.
摘要
产气气杆菌通过由磷酸转移酶系统启动的诱导途径异化甘露醇，该磷酸转移酶系统依赖磷酸烯醇丙酮酸作为磷酰基供体。该途径中的突变阻断可以在表型水平上通过诱导d-阿拉伯糖醇脱氢酶来抑制，d-阿拉伯糖醇脱氢酶是一种偶然能够将甘露醇转化为果糖的酶，或者在基因型水平上通过d-阿拉伯糖醇系统中的组成型突变来抑制。
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Replacement of a phosphoenolpyruvate-dependent phosphotransferase by a nicotinamide adenine dinucleotide-linked dehydrogenase for the utilization of mannitol.用烟酰胺腺嘌呤二核苷酸连接的脱氢酶替代磷酸烯醇丙酮酸依赖性磷酸转移酶以利用甘露醇。
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