MacLennan W J, Hamilton J C
J Clin Pathol. 1979 Mar;32(3):240-3. doi: 10.1136/jcp.32.3.240.
Plasma 25-hydroxy-vitamin D (25-OHD) concentrations and 25-OHD binding capacities were measured in 14 elderly patients and in 14 young controls. Both 25-OHD concentrations and 25-OHD binding capacities were reduced in the elderly. In neither group, however, was there a significant correlation between 25-OHD binding capacities and 25-OHD concentrations. Thus, although 25-OHD binding capacities are reduced in sick old people this does not account for the low 25-OHD concentrations often found in this group.
对14名老年患者和14名年轻对照者测量了血浆25-羟基维生素D(25-OHD)浓度及25-OHD结合能力。老年人的25-OHD浓度和25-OHD结合能力均降低。然而,两组中25-OHD结合能力与25-OHD浓度之间均无显著相关性。因此,尽管患病老年人的25-OHD结合能力降低,但这并不能解释该组中经常出现的低25-OHD浓度。