Gage P W, Moore J W
Science. 1969 Oct 24;166(3904):510-2. doi: 10.1126/science.166.3904.510.
Transmission in the giant synapse of squid was studied by measuring synaptic currents in the voltage-clamped postsynaptic giant axon. These currents varied linearly with the axon's membrane potential, and showed an intercept on the voltage axis at, or near, the sodium equilibrium potential. The intercept shifted in seawater containing less sodium by even more than the shift in the sodium equilibrium potential. It is concluded that the transmitter at this synapse causes a significant change in the sodium conductance only.
通过在电压钳制的突触后巨轴突中测量突触电流，对鱿鱼巨大突触中的传递进行了研究。这些电流随轴突膜电位呈线性变化，并且在钠平衡电位处或其附近的电压轴上显示出截距。在含钠量较少的海水中，截距的移动甚至比钠平衡电位的移动还要大。得出的结论是，该突触处的递质仅引起钠电导的显著变化。
