在自发性白血病发病率高的小鼠中，骨细胞形成病毒样颗粒。
Formation of virus-like particles by bone cells in mice with a high incidence of spontaneous leukemia.
作者信息
Schofield B H, Barrett C P, Doty S B, Figge F H, Robinson R A
出版信息
Science. 1970 May 1;168(3931):588-9. doi: 10.1126/science.168.3931.588.
PMID:4314271
Abstract
Bone samples from potentially leukemic and leukemic mice revealed numerous 90-to 110-nanometer particles morphologically identical to murine leukemia virus. Particles were observed budding from plasma membranes of osteocytes and osteoblasts but were most numerous in osteocyte lacunae. Particles were not observed in bone samples from mice which rarely develop leukemia.
摘要
来自潜在白血病小鼠和白血病小鼠的骨样本显示出大量90至110纳米的颗粒，其形态与鼠白血病病毒相同。观察到颗粒从骨细胞和成骨细胞的质膜出芽，但在骨细胞腔中数量最多。在很少发生白血病的小鼠的骨样本中未观察到颗粒。
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