Morris J S, Ajdukiewicz A B, Read A E
Gut. 1970 Jul;11(7):549-54. doi: 10.1136/gut.11.7.549.
An investigation into the incidence of neurological disorder in 30 patients with adult coeliac disease has shown that three patients had severe depression, two had epileptiform convulsions, and one patient only had signs of involvement of the peripheral nervous system. Motor nerve conduction velocity was low in only one patient. When the nerve conduction velocities of the group on a gluten-free diet were compared with the group who were not on a gluten-free diet, there was no statistically significant difference. Similarly, nerve conduction velocities in patients with a low serum pyridoxal level were not significantly different from those with normal serum pyridoxal levels. Measurements of the serum level of pyridoxal in 30 patients confirmed that pyridoxine deficiency occurs in adult coeliac disease and that the restriction of gluten from the diet appeared to affect pyridoxal levels favourably.
一项针对30例成人乳糜泻患者神经障碍发病率的调查显示，3例患者患有严重抑郁症，2例有癫痫样惊厥，仅1例患者有周围神经系统受累迹象。仅1例患者运动神经传导速度较低。将采用无麸质饮食组的神经传导速度与未采用无麸质饮食组进行比较，差异无统计学意义。同样，血清吡哆醛水平低的患者与血清吡哆醛水平正常的患者的神经传导速度也无显著差异。对30例患者血清吡哆醛水平的测量证实，成人乳糜泻患者存在吡哆醇缺乏，饮食中限制麸质似乎对吡哆醛水平有有利影响。
