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洗必泰对人疱疹病毒、脊髓灰质炎病毒和腺病毒毒株的杀病毒活性。

Virucidal activity of chlorhexidine on strains of Herpesvirus hominis, poliovirus, and adenovirus.

作者信息

Bailey A, Longson M

出版信息

J Clin Pathol. 1972 Jan;25(1):76-8. doi: 10.1136/jcp.25.1.76.

Abstract

The infectivity titre of two strains of Herpesvirus hominis was reduced by not more than six log(10) units by 90 minutes' exposure to chlorhexidine at a final concentration of 0.02% at room temperature. Under identical conditions the compound was ineffective against a vaccine strain of poliovirus and against an adenovirus. Experimental conditions are described whereby the toxic effect of the disinfectant on the tissue culture assay systems are minimized.

摘要

在室温下,将两株人疱疹病毒暴露于终浓度为0.02%的氯己定90分钟,其感染性滴度降低不超过6个对数(10)单位。在相同条件下,该化合物对脊髓灰质炎病毒疫苗株和腺病毒无效。文中描述了实验条件,据此可将消毒剂对组织培养测定系统的毒性作用降至最低。

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本文引用的文献

1
The inactivation of herpessimplex virus by chemical agents.
Am J Ophthalmol. 1961 Jan;51:42-57. doi: 10.1016/0002-9394(61)91310-1.
3
Infection of the vulva and cervix with a genital strain of herpes simplex virus.
J Obstet Gynaecol Br Commonw. 1968 Jul;75(7):768-74. doi: 10.1111/j.1471-0528.1968.tb01561.x.
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Herpes-simplex-virus infection after renal transplantation.肾移植后的单纯疱疹病毒感染
Lancet. 1969 Oct 25;2(7626):867-71. doi: 10.1016/s0140-6736(69)92327-7.

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