爱泼斯坦-巴尔病毒感染中病毒脱氧核糖核酸的复制及细胞脱氧核糖核酸的分解
Replication of viral deoxyribonucleic acid and breakdown of cellular deoxyribonucleic acid in Epstein-Barr virus infection.
作者信息
Nonoyama M, Pagano J S
出版信息
J Virol. 1972 Apr;9(4):714-6. doi: 10.1128/JVI.9.4.714-716.1972.
Abstract
Infection of Raji cells with Epstein-Barr virus (EBV) causes suppression of cellular deoxyribonucleic acid (DNA) synthesis and fragmentation of the cellular DNA. About 1,000 copies of EBV DNA of normal size (about 5 x 10(7) daltons in a single strand, as shown in an alkaline gradient) are synthesized per cell.
摘要
用爱泼斯坦-巴尔病毒（EBV）感染拉吉细胞会导致细胞脱氧核糖核酸（DNA）合成受抑制以及细胞DNA片段化。每个细胞会合成约1000份正常大小的EBV DNA（如在碱性梯度中所示，单链约为5×10⁷道尔顿）。
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本文引用的文献
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Transformation and chromosome changes induced by Epstein-Barr virus in normal human leukocyte cultures.爱泼斯坦-巴尔病毒在正常人白细胞培养物中诱导的转化和染色体变化。
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Host cell macromolecular synthesis in cells containing EBV-induced early antigens, studied by combined immunofluorescence and radioautography.通过联合免疫荧光和放射自显影术研究含有EB病毒诱导早期抗原的细胞中宿主细胞的大分子合成。
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