菲律宾尼格利陀人的群体遗传学研究。II. 三个群体的免疫球蛋白重链γ（gm）和免疫球蛋白轻链κ（km）同种异型
Population genetic studies of the Philippine Negritos. II. gm and km allotypes of three population groups.
作者信息
Matsumoto H, Miyazaki T, Omoto K, Misawa S, Harada S, Hirai M, Sumpaico J S, Medado P M, Ogonuki H
出版信息
Am J Hum Genet. 1979 Jan;31(1):70-6.
Serum samples of the three tribal Negrito populations in the Philippine Islands (127 from Zambales, 87 from Bataan, and 93 from Agusan) were tested for Glm(1,2,3 and 17), and G3m(5,6,11,13,14,15,16, and 21), and Km(1). The GMpatterm of the Negritos is characterized by three haplotypes, Gm1,17;21, Gm1,2,17;21, and Gm1,3;5,11,13,14, which is also characteristic of Mongoloid-related populations, especially with high incidence of the latter haplotype. They also have the haplotype, Gm1,17;5,13,14, prevalent in Africa, New Guinea, and northern Australia, suggesting an ancient link between the Negritos and the New Guinean-Australian group. Two unusual samples of G3m(15) positive without G3m(16) observed in Zambales Negritos suggest the presence of Gm1,17;5,11,13,14,15 haplotype in the population. This appears to be unique to Zambales Negritos and the first such samples to be found.
对菲律宾群岛三个部落尼格利陀人群的血清样本（赞巴莱斯127份、巴丹87份、阿古桑93份）进行了Glm(1,2,3和17)、G3m(5,6,11,13,14,15,16和21)以及Km(1)检测。尼格利陀人的GM模式具有三种单倍型特征，即Gm1,17;21、Gm1,2,17;21和Gm1,3;5,11,13,14，这也是与蒙古人种相关人群的特征，尤其是后一种单倍型的高发生率。他们还具有在非洲、新几内亚和澳大利亚北部普遍存在的单倍型Gm1,17;5,13,14，这表明尼格利陀人与新几内亚 - 澳大利亚人群之间存在古老的联系。在赞巴莱斯尼格利陀人中观察到两个不寻常的G3m(15)阳性且无G3m(16)的样本，这表明该人群中存在Gm1,17;5,11,13,14,15单倍型。这似乎是赞巴莱斯尼格利陀人所特有的，也是首次发现此类样本。
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