Chan W C, Colbourne M J, Fung S C, Ho H C
Br J Cancer. 1979 Feb;39(2):182-92. doi: 10.1038/bjc.1979.29.
Bronchial cancer is a disease of high and increasing annual incidence in Hong Kong, especially in women, whose age-specific death rates from this cause are amongst the highest in the world. A case-control study of the relationship of bronchial cancer with smoking was carried out during 1976--77, taking particular note of the histological type of the tumour. Two hundred and eight male and 189 female patients were interviewed, covering about half the total number of cases of bronchial cancer registered as dead from the disease in Hong Kong during the period of the survey. The association with smoking was more evident in males than in females, and in squamous and small-cell types, as a group, than in adenocarcinoma. Forty-four per cent of the women with bronchial cancer were non-smokers, their predominant tumour being adenocarcinoma, and in them on association could be detected with place of residence or occupation. There was no strong evidence of an association with the use of kerosene or gas for cooking; 23 did not use kerosene. The cause of the cancer in these non-smoking women remains unknown.
支气管癌在香港是一种年发病率高且呈上升趋势的疾病,尤其是在女性中,其按年龄划分的因该病因导致的死亡率位居世界前列。1976年至1977年期间,开展了一项关于支气管癌与吸烟关系的病例对照研究,特别关注肿瘤的组织学类型。对208名男性和189名女性患者进行了访谈,涵盖了调查期间香港登记因该疾病死亡的支气管癌病例总数的约一半。吸烟与支气管癌的关联在男性中比在女性中更明显,在鳞状细胞癌和小细胞癌类型中总体上比在腺癌中更明显。44%的患支气管癌的女性不吸烟,她们主要患的是腺癌,在她们身上未发现与居住地点或职业有关联。没有有力证据表明与使用煤油或煤气烹饪有关联;23人不使用煤油。这些不吸烟女性患癌的原因仍然不明。