Dickson W, Hall C E, Ellis M, Horrocks R H
Arch Dis Child. 1973 Sep;48(9):671-5. doi: 10.1136/adc.48.9.671.
Twenty-five patients with severe childhood asthma were treated with beclomethasone dipropionate. 21 of these children were receiving oral corticosteroid therapy in addition to disodium cromoglycate. Of the total treated, 21 children improved or maintained their asthma status on this treatment over an average period of 4 months, and were able to reduce and stop their regular oral corticosteroid dosage, but 4 children had to revert to their original therapy. No systemic or local toxic effects were experienced by any of the children. Beclomethasone dipropionate appears to be an effective drug in the treatment of severe childhood asthma in those patients who need corticosteroid therapy in addition to disodium cromoglycate.
25例重度儿童哮喘患者接受了二丙酸倍氯米松治疗。其中21名儿童除接受色甘酸钠治疗外,还在接受口服皮质类固醇治疗。在全部接受治疗的患者中,21名儿童在平均4个月的治疗期内哮喘病情得到改善或维持,并且能够减少并停用常规口服皮质类固醇药物剂量,但有4名儿童不得不恢复原来的治疗方案。所有儿童均未出现全身或局部毒性反应。对于那些除色甘酸钠外还需要皮质类固醇治疗的重度儿童哮喘患者,二丙酸倍氯米松似乎是一种有效的治疗药物。