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劳氏肉瘤病毒DNA合成的病毒体相关RNA引物：从未感染细胞中分离得到

Virion-associated RNA primer for Rous sarcoma virus DNA synthesis: isolation from uninfected cells.

作者信息

Sawyer R C, Harada F, Dahlberg J E

出版信息

J Virol. 1974 Jun;13(6):1302-11. doi: 10.1128/JVI.13.6.1302-1311.1974.

DOI:10.1128/JVI.13.6.1302-1311.1974
PMID:4364902
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC355449/
Abstract

Uninfected chicken, duck, rat, and human fibroblast cells in culture contained a tRNA-like RNA molecule which was structurally identical to a virion-associated RNA primer for in vitro Rous sarcoma virus DNA synthesis. This primer RNA appeared to be a normal tRNA of these cells. It was not found in a number of lower eukaryotic cells or in Escherichia coli.

摘要

培养中的未感染鸡、鸭、大鼠和人成纤维细胞含有一种类似tRNA的RNA分子，其结构与体外罗氏肉瘤病毒DNA合成的病毒体相关RNA引物相同。这种引物RNA似乎是这些细胞的正常tRNA。在许多低等真核细胞或大肠杆菌中未发现它。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0438/355449/0031d9e08c90/jvirol00246-0165-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0438/355449/370a4a3058ac/jvirol00246-0160-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0438/355449/381e20095f29/jvirol00246-0161-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0438/355449/9e13efce539c/jvirol00246-0163-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0438/355449/ec2bc4593d81/jvirol00246-0163-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0438/355449/0031d9e08c90/jvirol00246-0165-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0438/355449/370a4a3058ac/jvirol00246-0160-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0438/355449/381e20095f29/jvirol00246-0161-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0438/355449/9e13efce539c/jvirol00246-0163-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0438/355449/ec2bc4593d81/jvirol00246-0163-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0438/355449/0031d9e08c90/jvirol00246-0165-a.jpg

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本文引用的文献

1
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2
Protein metabolism in cultured plant tissues. Calculation of an absolute rate of protein synthesis, accumulation, and degradation in tobacco callus in vivo.培养植物组织中的蛋白质代谢。体内烟草愈伤组织中蛋白质合成、积累和降解绝对速率的计算。
Biochemistry. 1971 Jan 5;10(1):81-8. doi: 10.1021/bi00777a013.
3
A two-dimensional fractionation procedure for radioactive nucleotides.
慢病毒RNA上从tRNA(3Lys)起始(-)链DNA合成：特定HIV-1 RNA-tRNA(3Lys)相互作用对逆转录病毒逆转录酶引物利用的抑制作用
Proc Natl Acad Sci U S A. 1996 Sep 17;93(19):10063-8. doi: 10.1073/pnas.93.19.10063.
4
Identification of tRNAs incorporated into wild-type and mutant human immunodeficiency virus type 1.整合到野生型和突变型人类免疫缺陷病毒1型中的转运RNA的鉴定
J Virol. 1993 Jun;67(6):3246-53. doi: 10.1128/JVI.67.6.3246-3253.1993.
5
Polyacrylamide gel mapping of chicken tRNA: comparison of polysome-bound and whole-cell tRNA from normal and avian sarcoma virus-infected chicken embryo fibroblasts.鸡tRNA的聚丙烯酰胺凝胶图谱分析：正常和禽肉瘤病毒感染的鸡胚成纤维细胞中多核糖体结合tRNA与全细胞tRNA的比较
Mol Cell Biol. 1982 Oct;2(10):1247-57. doi: 10.1128/mcb.2.10.1247-1257.1982.
6
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Nucleic Acids Res. 1983 Jul 25;11(14):4823-33. doi: 10.1093/nar/11.14.4823.
7
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9
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J Mol Biol. 1973 Sep 5;79(1):163-83. doi: 10.1016/0022-2836(73)90277-5.
9
Methionine transfer ribonucleic acids of avian myeloblastosis virus.禽成髓细胞瘤病毒的甲硫氨酸转移核糖核酸
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