在口蹄疫地方流行区重复接种疫苗对带毒牛发生率的影响
The effect of repeated vaccination in an enzootic foot-and-mouth disease area on the incidence of virus carrier cattle.
作者信息
Anderson E C, Doughty W J, Anderson J
出版信息
J Hyg (Lond). 1974 Oct;73(2):229-35. doi: 10.1017/s0022172400024062.
Abstract
A comparison was made of the incidence of foot-and-mouth disease virus ;carrier' cattle in an unvaccinated enzootic area and an area where routine 6-monthly vaccination with an inactivated vaccine had been carried out for 3-4 years. The incidence of carriers in the vaccinated area was 0.49% as compared to 3.34% in the non-vaccinated area. The results indicate that, provided the immune status of the vaccinated herd is maintained at a level sufficient to prevent outbreaks of clinical disease and the re-introduction of virus is prevented through livestock movement controls, it should be possible to eradicate the disease from an enzootic area through vaccination.
摘要
对未接种疫苗的地方流行区和已进行3至4年每6个月常规接种灭活疫苗的地区口蹄疫病毒“带毒”牛的发生率进行了比较。接种疫苗地区带毒牛的发生率为0.49%，而未接种疫苗地区为3.34%。结果表明，如果接种疫苗牛群的免疫状态维持在足以预防临床疾病暴发的水平，并且通过牲畜流动控制防止病毒再次传入，那么通过接种疫苗应该有可能在地方流行区根除该疾病。
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