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Dihydrofolate reductase. Purification and characterization of the enzyme from an amethopterin-resistant mutant of Escherichia coli.

作者信息

Poe M, Greenfield N J, Hirshfield J M, Williams M N, Hoogsteen K

出版信息

Biochemistry. 1972 Mar 14;11(6):1023-30. doi: 10.1021/bi00756a012.

DOI:10.1021/bi00756a012
PMID:4401227
Abstract
摘要

相似文献

1
Dihydrofolate reductase. Purification and characterization of the enzyme from an amethopterin-resistant mutant of Escherichia coli.二氢叶酸还原酶。从大肠杆菌氨甲蝶呤抗性突变体中纯化并鉴定该酶。
Biochemistry. 1972 Mar 14;11(6):1023-30. doi: 10.1021/bi00756a012.
2
Purification and properties of dihydrofolate reductase from an amethopterin-resistant strain of Streptococcus faecium.来自耐氨甲蝶呤粪肠球菌菌株的二氢叶酸还原酶的纯化及性质
Biochemistry. 1972 Apr 11;11(8):1528-34. doi: 10.1021/bi00758a030.
3
Dihydrofolate reductase from amethopterin-resistant Lactobacillus casei.来自氨甲蝶呤抗性干酪乳杆菌的二氢叶酸还原酶。
Biochemistry. 1972 Mar 14;11(6):1018-23. doi: 10.1021/bi00756a011.
4
Dihydrofolate reductases of Escherichia coli and bacteriophage Tr. A spectrofluorometric study.
Biochemistry. 1973 Jan 30;12(3):372-80. doi: 10.1021/bi00727a002.
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Methotrexate binding to dihydrofolate reductase from a methotrexate-resistant strain of Escherichia coli.甲氨蝶呤与来自耐甲氨蝶呤大肠杆菌菌株的二氢叶酸还原酶的结合
J Biol Chem. 1973 Sep 25;248(18):6375-9.
6
Purification and properties of Escherichia coli dihydrofolate reductase.大肠杆菌二氢叶酸还原酶的纯化及性质
Biochemistry. 1975 Dec 2;14(24):5267-73. doi: 10.1021/bi00695a006.
7
Metabolic control of synthesis of the different forms of dihydrofolate reductase of the amethopterin-resistant Streptococcus faecium var. durans A k .氨甲蝶呤抗性粪肠球菌变种耐久肠球菌A k不同形式二氢叶酸还原酶合成的代谢控制
Arch Biochem Biophys. 1972 Nov;153(1):16-25. doi: 10.1016/0003-9861(72)90415-8.
8
Affinity chromatography of dihydrofolate reductase.二氢叶酸还原酶的亲和层析
Biochem J. 1971 Aug;124(1):1-12. doi: 10.1042/bj1240001.
9
Implication of a tryptophyl residue in the active site of dihydrofolate reductase.色氨酸残基在二氢叶酸还原酶活性位点中的作用。
Biochemistry. 1974 Apr 23;13(9):1807-14. doi: 10.1021/bi00706a005.
10
The purification and properties of the trimethoprim-resistant dihydrofolate reductase mediated by the R-factor, R388.由R因子R388介导的耐甲氧苄啶二氢叶酸还原酶的纯化及特性
Eur J Biochem. 1976 Jan 15;61(2):597-603. doi: 10.1111/j.1432-1033.1976.tb10055.x.

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Modulating Enzyme Activity by Altering Protein Dynamics with Solvent.通过溶剂改变蛋白质动力学来调节酶活性
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Moritella cold-active dihydrofolate reductase: are there natural limits to optimization of catalytic efficiency at low temperature?
嗜冷栖热袍菌冷活性二氢叶酸还原酶:在低温下催化效率的优化是否存在天然限制?
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Synergism in replication and translation of messenger RNA in a cell-free system.
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Cloning and molecular analysis of the dihydrofolate reductase gene from Lactococcus lactis.乳酸乳球菌二氢叶酸还原酶基因的克隆与分子分析
Appl Environ Microbiol. 1995 Feb;61(2):561-6. doi: 10.1128/aem.61.2.561-566.1995.
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Antibodies specific for NADPH-binding region of enzymes possessing dehydrogenase activities.针对具有脱氢酶活性的酶的NADPH结合区域的特异性抗体。
Proc Natl Acad Sci U S A. 1983 Mar;80(5):1221-3. doi: 10.1073/pnas.80.5.1221.
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Purification and properties of dihydrofolate reductase from cultured mammalian cells.来自培养哺乳动物细胞的二氢叶酸还原酶的纯化及性质
Biochem J. 1973 Jun;133(2):349-56. doi: 10.1042/bj1330349.
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Purification of nucleotide-requiring enzymes by immunoaffinity chromatography.通过免疫亲和层析法纯化核苷酸需求酶。
Biochem J. 1985 Mar 15;226(3):653-9. doi: 10.1042/bj2260653.
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Construction of a fol mutant strain of Escherichia coli for use in dihydrofolate reductase mutagenesis experiments.构建用于二氢叶酸还原酶诱变实验的大肠杆菌叶酸突变株。
J Bacteriol. 1988 Jul;170(7):3301-4. doi: 10.1128/jb.170.7.3301-3304.1988.
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Characterization of a staphylococcal trimethoprim resistance gene and its product.一种葡萄球菌甲氧苄啶抗性基因及其产物的特性分析。
Antimicrob Agents Chemother. 1987 Jul;31(7):1027-32. doi: 10.1128/AAC.31.7.1027.