Bellamy D, Collins J V
Thorax. 1979 Feb;34(1):36-9. doi: 10.1136/thx.34.1.36.
Forty-four adult patients with acute severe asthma were studied on admission to a general hospital to determine the mode of presentation and clinical severity of the acute illness. Most patients described poorly controlled wheezing for a mean period of five weeks before a more rapid deterioration, usually over 24 hours, caused them to seek medical attention. The clinical severity of the acute attach was not related to the duration of acute wheezing before admission to hospital. Recovery, studied in 11 of the patients, was slow, and most had reached only 70% of their predicted spirometric values after seven days' treatment in hospital. The rate of recovery was not influenced by the antecedent history of acute wheezing. Very sudden deterioration from a background of good control appears to be uncommon in adults with asthma who present to hospital as emergencies, and it is likely that improvement in the standard of routine management of asthmatics at home would prevent many such admissions.
对44名急性重症哮喘成年患者在一家综合医院入院时进行了研究,以确定急性疾病的表现方式和临床严重程度。大多数患者表示在病情迅速恶化(通常在24小时内)导致他们寻求医疗救助之前,喘息控制不佳平均持续了五周。急性发作的临床严重程度与入院前急性喘息的持续时间无关。对11名患者的恢复情况进行研究发现,恢复缓慢,大多数患者在住院治疗七天后,其肺量计预测值仅达到70%。恢复速度不受急性喘息既往史的影响。在因紧急情况入院的成年哮喘患者中,从良好控制的背景下非常突然地恶化似乎并不常见,并且在家中哮喘患者常规管理标准的改善可能会防止许多此类入院情况的发生。