Kirwan W O, Smith A N, McConnell A A, Mitchell W D, Eastwood M A
Br Med J. 1974 Oct 26;4(5938):187-9. doi: 10.1136/bmj.4.5938.187.
Two different types of commercially available bran were studied. One of these was composed of flake-like particles (coarse bran) whereas the other had smaller, finer particles with a floury component (fine bran). The effectiveness of the two preparations in lowering intraluminal pressure and decreasing transit time in patients with constipation and diverticular disease was assessed. Only coarse bran promoted changes at the dose used. The physical properties of the brans were examined in an effort to explain their differing effects. It is concluded that water-holding capacity, upon which the beneficial effect of bran may depend, is a function of particle size. The greater water-holding capacity of coarse bran makes it preferable for the treatment of colonic disorders.
对两种不同类型的市售麸皮进行了研究。其中一种由片状颗粒组成（粗麸皮），而另一种具有较小、更细的颗粒且带有粉质成分（细麸皮）。评估了这两种制剂对便秘和憩室病患者降低腔内压力和缩短转运时间的有效性。仅粗麸皮在所使用的剂量下促进了变化。对麸皮的物理性质进行了研究，以解释它们不同的效果。得出的结论是，麸皮的有益作用可能依赖的持水能力是颗粒大小的函数。粗麸皮更大的持水能力使其更适合用于治疗结肠疾病。
