Srivastava G S, Smith A N, Painter N S
Br Med J. 1976 Feb 7;1(6005):315-8. doi: 10.1136/bmj.1.6005.315.
Sterculia with and without a smooth-muscle relaxant (alverine citrate) had similar beneficial effects on constipation and reduced the transit times in diverticular disease. Intracolonic pressure, however, varied with the preparation used. Though both preparations relieved the symptoms of diverticular disease, the one containing alverine citrate was more effective. Part of the mode of action of bran may be to relax the smooth muscle of the gut, since its actions were more comparable to those of sterculia plus alverine citrate than to those of sterculia alone.
有无平滑肌松弛剂(枸橼酸阿尔维林)的苹婆对便秘有相似的有益效果,并缩短了憩室病患者的转运时间。然而,结肠内压力会因所用制剂的不同而有所变化。虽然两种制剂都缓解了憩室病的症状,但含有枸橼酸阿尔维林的制剂效果更佳。麸皮的部分作用方式可能是使肠道平滑肌松弛,因为其作用与含有枸橼酸阿尔维林的苹婆更相似,而与单独使用苹婆的情况不同。