Kreitmann B, Moure C, Bayard F
Ann Endocrinol (Paris). 1979 Jan-Feb;40(1):41-2.
The concentration of specific progesterone receptor (RP) has been measured in the endometrium of 31 normal menstruating women during the two phases of their menstrual cycle, and compared with the plasma oestradiol-17 beta (E2) concentrations. There was no relationship between RP and plasma E2 when the two phases of the cycle were considered, however a correlation was observed when the follicular phase was only considered. The relationship between oestrogen and RP was then more directly studied in a breast cancer cell line in tissue culture (MCF-7). RP induction by E2 as well as oestriol was demonstrated, but oestrone was ineffective.
已对31名正常月经周期女性在月经周期的两个阶段子宫内膜中的特异性孕酮受体（RP）浓度进行了测量，并与血浆雌二醇-17β（E2）浓度进行了比较。当考虑月经周期的两个阶段时，RP与血浆E2之间没有关系，然而，仅考虑卵泡期时观察到了相关性。然后在组织培养的乳腺癌细胞系（MCF-7）中更直接地研究了雌激素与RP之间的关系。证实了E2以及雌三醇可诱导RP，但雌酮无效。
