类风湿关节炎和干燥综合征患者血清及唾液中的IgA类风湿因子
IgA rheumatoid factor in the sera and saliva of patients with rheumatoid arthritis and Sjögren's syndrome.
作者信息
Dunne J V, Carson D A, Spiegelberg H L, Alspaugh M A, Vaughan J H
出版信息
Ann Rheum Dis. 1979 Apr;38(2):161-5. doi: 10.1136/ard.38.2.161.
Abstract
With a sensitive radioimmunoassay we have found elevated IgA rheumatoid factor (IgA-RF) levels in the sera of patients with rheumatoid arthritis, Sjögren's syndrome, and systemic lupus erythematosus. The IgA--RF showed a pattern of reaction with human IgG subclasses and animal gammaglobulins similar to that of IgM-RF from the same patients. Rheumatoid factors of both classes were shown to be present in saliva of patients with rheumatoid arthritis and Sjögren's syndrome.
摘要
通过一种灵敏的放射免疫测定法，我们发现类风湿关节炎、干燥综合征和系统性红斑狼疮患者血清中的IgA类风湿因子（IgA-RF）水平升高。IgA-RF与人类IgG亚类和动物丙种球蛋白的反应模式，与同一患者的IgM-RF相似。两类类风湿因子在类风湿关节炎和干燥综合征患者的唾液中均有存在。
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