链霉菌R39胞外DD-羧肽酶-转肽酶的分子量、氨基酸组成及理化性质
Molecular weight, amino acid composition and physicochemical properties of the exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R39.
作者信息
Frère J M, Moreno R, Ghuysen J M
出版信息
Biochem J. 1974 Oct;143(1):233-40. doi: 10.1042/bj1430233.
Abstract
The exocellular dd-carboxypeptidase-transpeptidase from Streptomyces R39 was purified to protein homogeneity and in milligram amounts. The isolated enzyme consisted of one polypeptide chain of molecular weight about 53300. Its amino acid composition and several physicochemical properties were determined and compared with those of the exo-cellular dd-carboxypeptidase-transpeptidase from Streptomyces R61.
摘要
来自链霉菌R39的细胞外双功能羧肽酶-转肽酶被纯化至蛋白质均一且达到毫克量。分离出的酶由一条分子量约为53300的多肽链组成。测定了其氨基酸组成和若干理化性质，并与来自链霉菌R61的细胞外双功能羧肽酶-转肽酶进行了比较。
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本文引用的文献
1
The oxidation of ribonuclease with performic acid.
J Biol Chem. 1956 Apr;219(2):611-21.
2
The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis.
J Biol Chem. 1969 Aug 25;244(16):4406-12.
3
Penicillin-sensitive DD-carboxypeptidases from Streptomyces strains R39 and K11.
Biochemistry. 1972 Mar 28;11(7):1290-8. doi: 10.1021/bi00757a027.
4
Penicillin-sensitive DD-carboxypeptidase from Streptomyces strain R 61.
Biochemistry. 1971 May 25;10(11):2163-70. doi: 10.1021/bi00787a032.
5
Fluorescence and circular dichroism studies on the Streptomyces R61 DD-carboxypeptidase-transpeptidase. Penicillin binding by the enzyme.
Biochem J. 1973 Nov;135(3):493-505. doi: 10.1042/bj1350493.
6
Kinetics of concomitant transfer and hydrolysis reactions catalysed by the exocellular DD-carboxypeptidase-transpeptidase of streptomyces R61.
Biochem J. 1973 Nov;135(3):483-92. doi: 10.1042/bj1350483.
7
Molecular weight and amino acid composition of the exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R61.
Biochem J. 1973 Nov;135(3):463-8. doi: 10.1042/bj1350463.
8
Streptomyces DD-carboxypeptidases as transpeptidases. The specificity for amino compounds acting as carboxyl acceptors.
Biochem J. 1973 Apr;131(4):707-18. doi: 10.1042/bj1310707.
9
Peptide inhibitors of Streptomyces DD-carboxypeptidases.
Biochem J. 1973 Jan;131(1):163-71. doi: 10.1042/bj1310163.
10
Structure of the wall peptidoglycan of Streptomyces R39 and the specificity profile of its exocellular DD-carboxypeptidase--transpeptidase for peptide acceptors.
Biochemistry. 1973 Mar 27;12(7):1243-51. doi: 10.1021/bi00731a001.
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