链霉菌R39胞外DD-羧肽酶-转肽酶的分子量、氨基酸组成及理化性质
Molecular weight, amino acid composition and physicochemical properties of the exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R39.
作者信息
Frère J M, Moreno R, Ghuysen J M
出版信息
Biochem J. 1974 Oct;143(1):233-40. doi: 10.1042/bj1430233.
Abstract
The exocellular dd-carboxypeptidase-transpeptidase from Streptomyces R39 was purified to protein homogeneity and in milligram amounts. The isolated enzyme consisted of one polypeptide chain of molecular weight about 53300. Its amino acid composition and several physicochemical properties were determined and compared with those of the exo-cellular dd-carboxypeptidase-transpeptidase from Streptomyces R61.
摘要
来自链霉菌R39的细胞外双功能羧肽酶-转肽酶被纯化至蛋白质均一且达到毫克量。分离出的酶由一条分子量约为53300的多肽链组成。测定了其氨基酸组成和若干理化性质，并与来自链霉菌R61的细胞外双功能羧肽酶-转肽酶进行了比较。
相似文献
1
Molecular weight, amino acid composition and physicochemical properties of the exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R39.链霉菌R39胞外DD-羧肽酶-转肽酶的分子量、氨基酸组成及理化性质
Biochem J. 1974 Oct;143(1):233-40. doi: 10.1042/bj1430233.
2
Molecular weight and amino acid composition of the exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R61.链霉菌R61胞外DD-羧肽酶-转肽酶的分子量及氨基酸组成
Biochem J. 1973 Nov;135(3):463-8. doi: 10.1042/bj1350463.
3
Binding of beta-lactam antibiotics to the exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R39.β-内酰胺抗生素与链霉菌R39的胞外D-羧肽酶-转肽酶的结合。
Biochem J. 1974 Oct;143(1):241-9. doi: 10.1042/bj1430241.
4
The exocellular DD-carboxypeptidase-endopeptidase from Streptomyces albus G. Purification and chemical properties.来自白色链霉菌G的胞外DD-羧肽酶-内肽酶。纯化及化学性质。
Biochem J. 1978 Dec 1;175(3):793-800. doi: 10.1042/bj1750793.
5
Mode of interaction between beta-lactam antibiotics and the exocellular DD-carboxypeptidase--transpeptidase from Streptomyces R39.β-内酰胺抗生素与来自链霉菌R39的细胞外DD-羧肽酶-转肽酶之间的相互作用模式
Biochem J. 1976 Jun 1;155(3):623-9. doi: 10.1042/bj1550623.
6
The exocellular beta-lactamase of Streptomyces albus G. Purification, properties and comparison with the exocellular DD-carboxypeptidase.白色链霉菌G的胞外β-内酰胺酶。纯化、性质及与胞外DD-羧肽酶的比较。
Biochem J. 1981 Jan 1;193(1):75-82. doi: 10.1042/bj1930075.
7
Exocellular DD-carboxypeptidases-transpeptidases from Streptomyces.
Methods Enzymol. 1976;45:610-36. doi: 10.1016/s0076-6879(76)45054-1.
8
Crystallographic data for a penicillin receptor : exocellular DD-carboxypeptidase-transpeptidase from Streptomyces R61.
J Mol Biol. 1979 Jan 15;127(2):217-8. doi: 10.1016/0022-2836(79)90241-9.
9
The peptidoglycan crosslinking enzyme system in Streptomyces strains R61, K15 and rimosus.
Eur J Biochem. 1977 Nov 15;81(1):19-28. doi: 10.1111/j.1432-1033.1977.tb11922.x.
10
Fragmentation of benzylpenicillin after interaction with the exocellular DD-carboxypeptidase-transpeptidases of Streptomyces R61 and R39.与链霉菌R61和R39的胞外DD-羧肽酶-转肽酶相互作用后苄青霉素的碎片化
Nature. 1975 Nov 13;258(5531):168-70. doi: 10.1038/258168a0.
引用本文的文献
1
Synthesis, purification and kinetic properties of fluorescein-labelled penicillins.荧光素标记青霉素的合成、纯化及动力学性质
Biochem J. 1994 May 15;300 ( Pt 1)(Pt 1):141-5. doi: 10.1042/bj3000141.
2
Kinetic study of interaction between BRL 42715, beta-lactamases, and D-alanyl-D-alanine peptidases.BRL 42715、β-内酰胺酶和D-丙氨酰-D-丙氨酸肽酶之间相互作用的动力学研究
Antimicrob Agents Chemother. 1995 Jan;39(1):227-31. doi: 10.1128/AAC.39.1.227.
3
Breakdown of the stereospecificity of DD-peptidases and beta-lactamases with thiolester substrates.DD-肽酶和β-内酰胺酶对硫酯底物的立体特异性分解
Biochem J. 1995 Jul 15;309 ( Pt 2)(Pt 2):431-6. doi: 10.1042/bj3090431.
4
Enzymatic method for rapid and sensitive determination of beta-lactam antibiotics.快速灵敏测定β-内酰胺类抗生素的酶法
Antimicrob Agents Chemother. 1980 Oct;18(4):506-10. doi: 10.1128/AAC.18.4.506.
5
Delta 2- and delta 3-cephalosporins, penicillinate and 6-unsubstituted penems. Intrinsic reactivity and interaction with beta-lactamases and D-alanyl-D-alanine-cleaving serine peptidases.δ2-和δ3-头孢菌素、青霉素酸盐及6-未取代青霉烯。内在反应活性以及与β-内酰胺酶和D-丙氨酰-D-丙氨酸裂解丝氨酸肽酶的相互作用。
Biochem J. 1982 Apr 1;203(1):223-34. doi: 10.1042/bj2030223.
6
Des-, syn- and anti-oxyimino-delta 3-cephalosporins. Intrinsic reactivity and reaction with RTEM-2 serine beta-lactamase and D-alanyl-D-alanine-cleaving serine and Zn2+-containing peptidases.去氧、顺式和反式氧亚氨基-δ3-头孢菌素。内在反应性以及与RTEM-2丝氨酸β-内酰胺酶、D-丙氨酰-D-丙氨酸裂解丝氨酸和含锌肽酶的反应。
Biochem J. 1984 Mar 15;218(3):933-7. doi: 10.1042/bj2180933.
7
Interaction between non-classical beta-lactam compounds and the Zn2+-containing G and serine R61 and R39 D-alanyl-D-alanine peptidases.非经典β-内酰胺化合物与含锌的G型和丝氨酸R61及R39 D-丙氨酰-D-丙氨酸肽酶之间的相互作用。
Biochem J. 1981 Oct 1;199(1):129-36. doi: 10.1042/bj1990129.
8
Binding of beta-lactam antibiotics to the exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R39.β-内酰胺抗生素与链霉菌R39的胞外D-羧肽酶-转肽酶的结合。
Biochem J. 1974 Oct;143(1):241-9. doi: 10.1042/bj1430241.
9
Unexpected influence of ionic strength on branched-pathway interactions between beta-lactamases and beta-halogenopenicillanates.离子强度对β-内酰胺酶与β-卤代青霉素酸之间分支途径相互作用的意外影响。
Biochem J. 1989 Jan 1;257(1):245-9. doi: 10.1042/bj2570245.
10
Chromogenic depsipeptide substrates for beta-lactamases and penicillin-sensitive DD-peptidases.用于β-内酰胺酶和对青霉素敏感的DD-肽酶的显色缩肽底物。
Biochem J. 1990 Sep 1;270(2):525-9. doi: 10.1042/bj2700525.
本文引用的文献
1
The oxidation of ribonuclease with performic acid.用过甲酸氧化核糖核酸酶。
J Biol Chem. 1956 Apr;219(2):611-21.
2
The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis.通过十二烷基硫酸钠-聚丙烯酰胺凝胶电泳测定分子量的可靠性。
J Biol Chem. 1969 Aug 25;244(16):4406-12.
3
Penicillin-sensitive DD-carboxypeptidases from Streptomyces strains R39 and K11.来自链霉菌菌株R39和K11的青霉素敏感型DD-羧肽酶
Biochemistry. 1972 Mar 28;11(7):1290-8. doi: 10.1021/bi00757a027.
4
Penicillin-sensitive DD-carboxypeptidase from Streptomyces strain R 61.来自链霉菌菌株R 61的青霉素敏感型DD-羧肽酶
Biochemistry. 1971 May 25;10(11):2163-70. doi: 10.1021/bi00787a032.
5
Fluorescence and circular dichroism studies on the Streptomyces R61 DD-carboxypeptidase-transpeptidase. Penicillin binding by the enzyme.链霉菌R61 D-羧肽酶-转肽酶的荧光和圆二色性研究。该酶与青霉素的结合。
Biochem J. 1973 Nov;135(3):493-505. doi: 10.1042/bj1350493.
6
Kinetics of concomitant transfer and hydrolysis reactions catalysed by the exocellular DD-carboxypeptidase-transpeptidase of streptomyces R61.链霉菌R61胞外DD-羧肽酶-转肽酶催化的伴随转移和水解反应的动力学
Biochem J. 1973 Nov;135(3):483-92. doi: 10.1042/bj1350483.
7
Molecular weight and amino acid composition of the exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R61.链霉菌R61胞外DD-羧肽酶-转肽酶的分子量及氨基酸组成
Biochem J. 1973 Nov;135(3):463-8. doi: 10.1042/bj1350463.
8
Streptomyces DD-carboxypeptidases as transpeptidases. The specificity for amino compounds acting as carboxyl acceptors.作为转肽酶的链霉菌DD-羧肽酶。对充当羧基受体的氨基化合物的特异性。
Biochem J. 1973 Apr;131(4):707-18. doi: 10.1042/bj1310707.
9
Peptide inhibitors of Streptomyces DD-carboxypeptidases.链霉菌DD-羧肽酶的肽类抑制剂。
Biochem J. 1973 Jan;131(1):163-71. doi: 10.1042/bj1310163.
10
Structure of the wall peptidoglycan of Streptomyces R39 and the specificity profile of its exocellular DD-carboxypeptidase--transpeptidase for peptide acceptors.链霉菌R39细胞壁肽聚糖的结构及其胞外DD-羧肽酶-转肽酶对肽受体的特异性谱
Biochemistry. 1973 Mar 27;12(7):1243-51. doi: 10.1021/bi00731a001.
Zotero 插件