霍乱弧菌扩展连锁图谱。
Expanded linkage map of Vibrio cholerae.
作者信息
Parker C, Gauthier D, Tate A, Richardson K, Romig W R
出版信息
Genetics. 1979 Feb;91(2):191-214. doi: 10.1093/genetics/91.2.191.
Abstract
An expanded linkage map of the Vibrio cholerae classical strain 162 chromosome has been prepared using a variety of new auxotrophic mutants. The chromosome consists of a single, linear linkage group. The map consists of 17 markers, which have been ordered; 20 mutational sites, which are tentatively ordered; five markers (ura-1, ser-2, mal-1, man-1, suc-1), which are linked but unordered; and three mutations (aro-2, cys-2 and cys-6) which showed little or no linkage. A proposal is made to standardize genetic nomenclature in V. cholerae genetic studies.
摘要
利用多种新的营养缺陷型突变体构建了霍乱弧菌古典生物型菌株162染色体的扩展连锁图谱。该染色体由一个单一的线性连锁群组成。该图谱包含17个已排序的标记、20个暂定排序的突变位点、5个连锁但未排序的标记（ura-1、ser-2、mal-1、man-1、suc-1）以及3个几乎没有连锁或无连锁的突变（aro-2、cys-2和cys-6）。文中提出了在霍乱弧菌遗传学研究中规范遗传命名法的建议。
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