金黄色葡萄球菌中耐甲氧西林的遗传决定因素导致环状质粒脱氧核糖核酸缺失。
Absence of circular plasmid deoxyribonucleic acid attributable to a genetic determinant for methicillin resistance in Staphylococcus aureus.
作者信息
Stiffler P W, Sweeney H M, Cohen S
出版信息
J Bacteriol. 1973 Nov;116(2):771-7. doi: 10.1128/jb.116.2.771-777.1973.
Abstract
Plasmid deoxyribonucleic acid was not detected by centrifugal analysis of lysates of penicillinase-negative strains of Staphylococcus aureus harboring a determinant of methicillin resistance derived from strain Villaluz. When these strains contained a penicillinase plasmid, the plasmid deoxyribonucleic acid of methicillin-resistant and methicillin-susceptible strains was indistinguishable by the methods employed. The results indicate that the genetic determinant for methicillin resistance in the strains examined was not associated with a circular plasmid comparable to those that have been shown to determine resistance to benzylpenicillin, tetracycline, and chloramphenicol in S. aureus.
摘要
对携带源自Villaluz菌株的耐甲氧西林决定簇的金黄色葡萄球菌青霉素酶阴性菌株的裂解物进行离心分析，未检测到质粒脱氧核糖核酸。当这些菌株含有青霉素酶质粒时，耐甲氧西林菌株和甲氧西林敏感菌株的质粒脱氧核糖核酸用所采用的方法无法区分。结果表明，所检测菌株中耐甲氧西林的遗传决定簇与一种环状质粒无关，这种环状质粒在金黄色葡萄球菌中已被证明可决定对苄青霉素、四环素和氯霉素的耐药性。
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本文引用的文献
1
Transduction of Methicillin Resistance in Staphylococcus aureus Dependent on an Unusual Specificity of the Recipient Strain.金黄色葡萄球菌中耐甲氧西林的转导取决于受体菌株的异常特异性。
J Bacteriol. 1970 Dec;104(3):1158-67. doi: 10.1128/jb.104.3.1158-1167.1970.
2
Sedimentation rate as a measure of molecular weight of DNA.沉降速率作为DNA分子量的一种衡量指标。
Biophys J. 1963 Jul;3(4):309-21. doi: 10.1016/s0006-3495(63)86823-x.
3
Circular dimer and catenate forms of mitochondrial DNA in human leukaemic leucocytes.人白血病白细胞中线粒体DNA的环状二聚体和连环体形式
Nature. 1967 Nov 18;216(5116):652-7. doi: 10.1038/216652a0.
4
Covalently closed minicircular DNA in Micrococcus lysodeikticus.溶壁微球菌中的共价闭合微小环状DNA。
Biochem Biophys Res Commun. 1968 Sep 6;32(5):757-62. doi: 10.1016/0006-291x(68)90304-5.
5
Simplified quantitative electron microscopy of biopolymers.生物聚合物的简化定量电子显微镜技术
Biopolymers. 1970;9(3):373-9. doi: 10.1002/bip.1970.360090310.
6
Genetic aspects of methicillin resistance and toxin production in a strain of Staphylococcus aureus.一株金黄色葡萄球菌中甲氧西林耐药性和毒素产生的遗传方面
Ann N Y Acad Sci. 1971 Jun 11;182:91-7. doi: 10.1111/j.1749-6632.1971.tb30647.x.
7
The problems of drug-resistant pathogenic bacteria. Extrachromosomal nature of drug resistance in Staphylococcus aureus.耐药病原菌的问题。金黄色葡萄球菌耐药性的染色体外性质。
Ann N Y Acad Sci. 1971 Jun 11;182:279-94. doi: 10.1111/j.1749-6632.1971.tb30664.x.
8
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9
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J Mol Biol. 1968 Sep 14;36(2):185-94. doi: 10.1016/0022-2836(68)90374-4.
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