从金黄色葡萄球菌中分离并鉴定一种卡那霉素抗性质粒。
Isolation and characterization of a kanamycin resistance plasmid from Staphylococcus aureus.
作者信息
Stiffler P W, Sweeney H M, Schneider M, Cohen S
出版信息
Antimicrob Agents Chemother. 1974 Oct;6(4):516-20. doi: 10.1128/AAC.6.4.516.
Abstract
A circular covalently closed duplex deoxyribonucleic acid plasmid carrying genes for resistance to kanamycin/neomycin has been identified in Staphylococcus aureus E419. The plasmid has a molecular size of 9.2 x 10(6) daltons and can be transduced into or can transform competent susceptible strains of S. aureus to kanamycin/neomycin resistance.
摘要
在金黄色葡萄球菌E419中发现了一种环状共价闭合双链脱氧核糖核酸质粒，它携带对卡那霉素/新霉素的抗性基因。该质粒的分子大小为9.2×10⁶道尔顿，可被转导到金黄色葡萄球菌的感受态敏感菌株中，或将其转化为对卡那霉素/新霉素具有抗性的菌株。
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