[太空飞行及伴随辐射对大鼠骨骼肌氨基酸代谢的影响]
[Effect of space flight and of the accompanying radiation on amino acid metabolism in the skeletal muscle of rats].
作者信息
Ushakov A S, Gaevskiĭ M S, Vlasova T F, Veresotskaia N A, Miroshnikova E B
出版信息
Kosm Biol Aviakosm Med. 1978 Jan-Feb;12(1):27-31.
It was demonstrated that a combined effect of 20.5-day space flight and gamma-irradiation reduced the content of biologically important amino acids (methionine, phenylalanine, serine, aspartic and glutamic acids) and inhibited the activity of aspartate aminotransferase of sarcoplasmatic proteins in the quadriceps muscle of rats. Comparison of these data with the Cosmos-605 results and literature reports suggested that gamma-irradiation inhibited the synthetic processes in the skeletal muscle.
结果表明，20.5天的太空飞行与γ辐射的联合作用降低了大鼠股四头肌中具有重要生物学意义的氨基酸（蛋氨酸、苯丙氨酸、丝氨酸、天冬氨酸和谷氨酸）的含量，并抑制了肌浆蛋白中天冬氨酸转氨酶的活性。将这些数据与“宇宙-605”号的结果及文献报道进行比较后表明，γ辐射抑制了骨骼肌中的合成过程。
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