部分肝切除大鼠血清对胎鼠肝细胞DNA和蛋白质合成的刺激作用。
Stimulation of DNA and protein synthesis in fetal-rat liver cells by serum from partially hepatectomized rats.
作者信息
Paul D, Leffert H, Sato G, Holley R W
出版信息
Proc Natl Acad Sci U S A. 1972 Feb;69(2):374-7. doi: 10.1073/pnas.69.2.374.
Abstract
Primary cultures of differentiated liver cells from fetal rats respond to serum from partially hepatectomized rats by an increased uptake of [(3)H]thymidine and [(3)H]leucine as compared with cultures incubated with normal rat serum. These findings are discussed in relation to the mechanism of induction of DNA synthesis and growth in liver cells during liver regeneration.
摘要
与用正常大鼠血清培养的细胞相比，来自胎鼠的分化肝细胞原代培养物对部分肝切除大鼠的血清反应为，[（3）H]胸苷和[（3）H]亮氨酸的摄取增加。结合肝再生过程中肝细胞DNA合成和生长的诱导机制对这些发现进行了讨论。
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Stimulation of DNA and protein synthesis in fetal-rat liver cells by serum from partially hepatectomized rats.部分肝切除大鼠血清对胎鼠肝细胞DNA和蛋白质合成的刺激作用。
Proc Natl Acad Sci U S A. 1972 Feb;69(2):374-7. doi: 10.1073/pnas.69.2.374.
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