小鼠λ链序列。
Mouse lambda-chain sequences.
作者信息
Cesari I M, Weigert M
出版信息
Proc Natl Acad Sci U S A. 1973 Jul;70(7):2112-6. doi: 10.1073/pnas.70.7.2112.
Abstract
Amino-acid sequences of the variable regions of three lambda chains produced by plasmacytomas of BALB/c mice are compared. Two are almost certainly identical and one differs from these by three amino acids. These findings extend our earlier conclusion on the relative uniformity of sequences in this type of immunoglobulin light chain. With amino-acid sequence data on two additional lambda chains, eight mouse lambda chains studied to date are indistinguishable and four probably differ from these by one, two, or three amino acids.
摘要
比较了BALB/c小鼠浆细胞瘤产生的三条λ链可变区的氨基酸序列。其中两条几乎肯定是相同的，另一条与它们有三个氨基酸的差异。这些发现扩展了我们之前关于此类免疫球蛋白轻链序列相对一致性的结论。根据另外两条λ链的氨基酸序列数据，迄今为止研究的八条小鼠λ链无法区分，另外四条可能与它们有一、二或三个氨基酸的差异。
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