住院及口服化疗对肠道大肠菌抗生素敏感性的影响。
Effect of stay in hospital and oral chemotherapy on the antibiotic sensitivity of bowel coliforms.
作者信息
Shaw E J, Datta N, Jones G, Marr F M, Froud W J
出版信息
J Hyg (Lond). 1973 Sep;71(3):529-34. doi: 10.1017/s0022172400046519.
Abstract
The effects of oral chemotherapy and stay in hospital on the antibiotic resistance patterns of faecal coliform flora were studied. The coliform flora of 64% of 25 patients who were not receiving antibiotics was sensitive to all drugs tested. Hospitalization alone did not affect this proportion. The administration of tetracycline or ampicillin to patients, whether at home or in hospital, significantly increased the percentage of resistant bowel coliforms. Tetracycline showed a significantly greater effect than ampicillin. There was no significant increase in the percentage of patients with resistant flora after treatment with amoxycillin.
摘要
研究了口服化疗和住院对粪便大肠菌群抗生素耐药模式的影响。25名未接受抗生素治疗患者中，64%的大肠菌群对所有测试药物敏感。仅住院并未影响这一比例。无论在家中还是医院，给患者使用四环素或氨苄西林都会显著增加耐药性肠道大肠菌群的比例。四环素的影响显著大于氨苄西林。阿莫西林治疗后，耐药菌群患者的比例没有显著增加。
相似文献
1
Effect of stay in hospital and oral chemotherapy on the antibiotic sensitivity of bowel coliforms.住院及口服化疗对肠道大肠菌抗生素敏感性的影响。
J Hyg (Lond). 1973 Sep;71(3):529-34. doi: 10.1017/s0022172400046519.
2
[Spread of extrachromosomal antibiotic resistance in the hospital].[医院中染色体外抗生素耐药性的传播]
Zentralbl Bakteriol Orig A. 1974;228(1):11-5.
3
The effect of R-factor carriage on the survival of Escherichia coli in the human intestine.R因子携带对大肠杆菌在人体肠道内存活的影响。
J Med Microbiol. 1974 Feb;7(1):85-90. doi: 10.1099/00222615-7-1-85.
4
The effect of hospitalization and antibiotic therapy on the gram-negative fecal flora.住院治疗和抗生素治疗对革兰氏阴性粪便菌群的影响。
Am J Med Sci. 1968 Apr;255:228-36. doi: 10.1097/00000441-196804000-00003.
5
Transmission of infectious drug resistance from animals to man.
J Hyg (Lond). 1973 Mar;71(1):209-15. doi: 10.1017/s0022172400046374.
6
Chemotherapy and antibiotic-resistance transfer between Enterobacteria in the human gastro-intestinal tract.人类胃肠道中肠杆菌之间的化疗与抗生素耐药性转移
J Med Microbiol. 1973 Nov;6(4):461-73. doi: 10.1099/00222615-6-4-461.
7
[The transmission of R factors in the human intestinal flora].[R因子在人类肠道菌群中的传播]
Zentralbl Bakteriol Orig. 1970;213(2):183-93.
8
Antibiotic resistance and transmissible R-factors in the intestinal coliform flora of healthy adults and children in an urban and a rural community.城市和农村社区健康成人及儿童肠道大肠菌群中的抗生素耐药性及可传递R因子
J Hyg (Lond). 1972 Mar;70(1):99-104. doi: 10.1017/s0022172400022130.
9
[Chemotherapy of respiratory diseases].[呼吸系统疾病的化疗]
Antibiotiki. 1971;16(8):743-9.
10
[Value in pulmonary diseases of a new broad spectrum semi-synthetic penicillin: amoxicillin].
Poumon Coeur. 1973;29(4):473-8.
引用本文的文献
1
Colonization and resistance dynamics of gram-negative bacteria in patients during and after hospitalization.住院期间及出院后患者革兰氏阴性菌的定植与耐药动态
Antimicrob Agents Chemother. 2005 Jul;49(7):2879-86. doi: 10.1128/AAC.49.7.2879-2886.2005.
2
A between-species comparison of antimicrobial resistance in enterobacteria in fecal flora.粪便菌群中肠杆菌科细菌抗菌药物耐药性的种间比较。
Antimicrob Agents Chemother. 2000 Jun;44(6):1479-84. doi: 10.1128/AAC.44.6.1479-1484.2000.
3
Problem of antimicrobial resistance of fecal aerobic gram-negative bacilli in the elderly.老年人粪便需氧革兰氏阴性杆菌的抗菌药物耐药性问题。
Antimicrob Agents Chemother. 1996 Oct;40(10):2399-403. doi: 10.1128/AAC.40.10.2399.
4
Screening for antimicrobial resistance in fecal samples by the replica plating method.通过影印接种法对粪便样本中的抗菌素耐药性进行筛查。
J Clin Microbiol. 1995 Dec;33(12):3146-9. doi: 10.1128/jcm.33.12.3146-3149.1995.
5
Antimicrobial resistance in human oral and intestinal anaerobic microfloras.人类口腔和肠道厌氧微生物群中的抗菌药物耐药性。
Antimicrob Agents Chemother. 1993 Aug;37(8):1665-9. doi: 10.1128/AAC.37.8.1665.
6
Trimethoprim resistance in South African isolates of aerobic gram-negative faecal flora.南非需氧革兰氏阴性粪便菌群分离株对甲氧苄啶的耐药性
Eur J Clin Microbiol Infect Dis. 1993 Dec;12(12):916-21. doi: 10.1007/BF01992165.
7
Beta-lactam resistance in aerobic faecal flora from general practice patients in the UK.英国全科医疗患者需氧粪便菌群中的β-内酰胺耐药性。
Eur J Clin Microbiol Infect Dis. 1994 Sep;13(9):760-3. doi: 10.1007/BF02276062.
8
Treatment of urinary tract infections with a combination of amoxicillin and clavulanic acid.阿莫西林与克拉维酸联合治疗尿路感染
Antimicrob Agents Chemother. 1982 Oct;22(4):672-7. doi: 10.1128/AAC.22.4.672.
9
Antibiotics I: new antibiotics and advances in antibiotic treatment.抗生素I：新型抗生素与抗生素治疗进展
Br Med J (Clin Res Ed). 1983 May 28;286(6379):1732-5. doi: 10.1136/bmj.286.6379.1732.
10
The digestive tract in immunocompromised patients: importance of maintaining its resistance to colonization, especially in hospital in-patients and those taking antibiotics.免疫功能低下患者的消化道：维持其抗定植能力的重要性，尤其是住院患者和正在服用抗生素的患者。
Antonie Van Leeuwenhoek. 1984;50(5-6):745-61. doi: 10.1007/BF02386238.
本文引用的文献
1
Drug resistance and R factors in the bowel bacteria of London patients before and after admission to hospital.伦敦患者入院前后肠道细菌中的耐药性与R因子
Br Med J. 1969 May 17;2(5654):407-11. doi: 10.1136/bmj.2.5654.407.
2
Transferable drug resistance in enterobacteria isolated from urban infants.从城市婴儿中分离出的肠道杆菌的可转移耐药性。
Br Med J. 1969 May 17;2(5654):405-7. doi: 10.1136/bmj.2.5654.405.
3
Amoxycillin: a new semi-synthetic penicillin.阿莫西林：一种新型半合成青霉素。
Br Med J. 1972 Jul 1;3(5817):13-6. doi: 10.1136/bmj.3.5817.13.
4
R Factors in Escherichia coli in faeces after oral chemotherapy in general practice.
Lancet. 1971 Feb 13;1(7694):312-5. doi: 10.1016/s0140-6736(71)91042-7.
Zotero 插件